Healthy volunteers help uncover hidden drug interactions

NCT ID NCT07196449

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 23 times

Summary

This study looks at how two common drugs, rifampicin and cyclosporine, change the way the body processes methotrexate. Healthy adult men will take methotrexate with one of these drugs, and blood samples will show how drug levels rise and fall. The goal is to understand potential interactions so methotrexate can be used more safely in the future.

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Contacts and locations

Locations

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggi-do, 13605, South Korea

Conditions

Explore the condition pages connected to this study.