Could a simple amino acid ease a devastating lung condition?

NCT ID NCT03887169

First seen Nov 20, 2025 · Last updated Jun 13, 2026 · Updated 22 times

Summary

This study tested whether giving methionine (an amino acid) by mouth or feeding tube is safe and tolerable for children with a severe, inherited lung disease called pulmonary alveolar proteinosis. The disease is caused by a faulty MARS gene that prevents cells from using methionine properly. Only 3 children took part, and the goal was to see if the supplement could improve breathing and reduce the need for lung washes.

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Contacts and locations

Locations

  • Hôpital Necker-Enfants Malades

    Paris, Île-de-France Region, 75015, France

Conditions

Explore the condition pages connected to this study.