IV iron drug may cause rare blood disorder, new study investigates
NCT ID NCT06958822
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at how often a rare blood condition called methemoglobinemia occurs after treatment with the IV iron drug ferric carboxymaltose. Researchers measured methemoglobin levels in nearly 1,000 adults receiving the drug for iron-deficiency anemia and compared them to healthy controls. The goal was to better understand the risk of this potentially serious side effect.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ferric carboxymaltose (IV iron)
What this could lead to
If this study finds a clear link, it could help doctors monitor for methemoglobinemia and make IV iron therapy safer.
What could go wrong
This is an observational study, not a controlled trial, so it can't prove cause and effect. The condition is rare and usually mild, so the findings may not change practice.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Akdeniz University Hospital
Konyaalti, Antalya, 07070, Turkey (Türkiye)
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Antalya City Hospital
Antalya, Kepez, 07080, Turkey (Türkiye)
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Balıkesir University Health Practice and Research Hospital
Merkez, Balıkesir, 10145, Turkey (Türkiye)
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Bursa City Hospital
Nilufer, Bursa, 16110, Turkey (Türkiye)
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Bursa Kestel State Hospital
Bursa, Kestel, 16450, Turkey (Türkiye)
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Bursa Yuksek Ihtisas Training and Research
Bursa, Yıldırım, 16310, Turkey (Türkiye)
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Izmir Bakircay University Cigli Training and Research Hospital
Çiğli, İzmir, 35610, Turkey (Türkiye)
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Karabuk University Training and Research Hospital
Karabük, Karabük Province, 78100, Turkey (Türkiye)
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Kayseri City Hospital
Kocasinan, Kayseri, 38080, Turkey (Türkiye)
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Mardin Artuklu University Training and Research Hospital
Merkez, Mardin, 47100, Turkey (Türkiye)
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Mardin Kızıltepe State Hospital
Mardin, Kızıltepe, 47400, Turkey (Türkiye)
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Marmara University Training and Research Hospital
Pendik, Istanbul, 34890, Turkey (Türkiye)
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Mehmet Yılmaz Aydınlar Acıbadem University
Ataşehir, Istanbul, 34758, Turkey (Türkiye)
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Ordu University Training and Research Hospital
Altinordu, Ordu, 52200, Turkey (Türkiye)
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Recep Tayyip Erdoğan University Faculty of Medicine Training and Research Hospital
Rize, Rize Province, 53100, Turkey (Türkiye)
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Sakarya University Training and Research Hospital
Adapazarı, Sakarya, 54100, Turkey (Türkiye)
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Siirt University Faculty of Medicine Training and Research Hospital
Siirt, Siirt, 56100, Turkey (Türkiye)
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Umraniye Training and Research Hospital
Ümraniye, Istanbul, 34764, Turkey (Türkiye)
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University of Health Sciences Adana City Health Application and Research Center
Adana, Adana, 01100, Turkey (Türkiye)
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University of Health Sciences Diyarbakır Gazi Yaşargil Training and Research Hospital
Kayapınar, Diyarbakır, 21070, Turkey (Türkiye)
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Van Yüzüncü Yıl University Training and Research Hospital
Merkez, Van, 65000, Turkey (Türkiye)
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Çankırı State Hospital
Çankırı, Çankırı, 18100, Turkey (Türkiye)
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Çorlu Vatan Hospital
Tekirdağ, Çorlu, 59850, Turkey (Türkiye)