One-Dose methadone may slash opioid use after hysterectomy

NCT ID NCT06536517

First seen Jan 05, 2026 · Last updated May 10, 2026 · Updated 29 times

Summary

This study tests whether giving a single dose of methadone during laparoscopic or robotic hysterectomy can reduce the need for opioid painkillers after surgery. About 100 adults with a uterus having the procedure for benign reasons will be randomly assigned to receive either methadone or standard short-acting opioids during surgery. The goal is to lower opioid use and prevent addiction.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Johns Hopkins Bayview Medical Center

    RECRUITING

    Baltimore, Maryland, 21224, United States

    Contact

  • The Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact

Conditions

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