Diabetes drug metformin tested to stop blood cancer before it starts
NCT ID NCT04850846
First seen Sep 30, 2025 · Last updated May 23, 2026 · Updated 27 times
Summary
This study tests whether metformin, a widely used diabetes medicine, can stop early blood conditions (MGUS and smoldering myeloma) from turning into multiple myeloma. About 60 people with higher-risk MGUS or low-risk smoldering myeloma will receive either metformin or a placebo pill. Researchers will track changes in blood protein levels and other markers over time to see if metformin can slow or prevent disease progression.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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DF/ BWCC in Clinical Affiliation with South Shore Hospital
Weymouth, Massachusetts, 02190, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Dana-Farber at Brighton
Brighton, Massachusetts, 02135, United States
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Dana-Farber at Merrimack Valley
Methuen, Massachusetts, 01844, United States
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Dana-Farber at Milford
Milford, Massachusetts, 01757, United States
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Dana-Farber at NHOH
Londonderry, New Hampshire, 35053, United States
Conditions
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