Common diabetes drug tested to help cystic fibrosis lungs
NCT ID NCT04530383
Summary
This study tested whether metformin, a common diabetes medication, could improve how cells in the airways work for adults with cystic fibrosis who also have diabetes. It was a small, terminated Phase 2 trial where participants took either a low or normal dose of metformin (or a placebo pill) for 14-week periods. The main goal was to see if the drug changed specific markers of ion channel function in nasal cells, which could indicate better lung health.
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Locations
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University of Kansas Medical Center
Kansas City, Kansas, 66160, United States
Conditions
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