Common diabetes drug may protect against amputation risk
NCT ID NCT04583462
Summary
This study is testing if metformin, a common diabetes medication, can slow the buildup of calcium in leg arteries (hardening) in people with long-term type 1 diabetes. Over two years, 230 participants will take either metformin or a placebo pill, and researchers will use leg CT scans to measure changes in artery calcification. The goal is to see if this treatment can help control a serious complication that increases the risk of heart problems and limb amputation.
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Contacts and locations
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Locations
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Pitié Salpêtrière Hospital, AP-HP, Diabetology department
Paris, 75013, France
Conditions
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