Diet breaks may wreck metabolism and gut bugs, study warns
NCT ID NCT06782009
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at what happens to the body when people with obesity stop following restrictive diets like calorie cutting or intermittent fasting. Researchers measured changes in mitochondria (the cell's energy factories) and gut bacteria in 84 adults over 24 weeks. The goal is to understand why weight regain often occurs and how it affects overall health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
calorie restriction and intermittent fasting
What this could lead to
If successful, this could help explain why weight regain happens after dieting and point to ways to prevent it.
What could go wrong
This is a small, completed observational study, not a treatment trial. Results may not apply to everyone and do not test a new therapy.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OBESITY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Departamento de Fisiología de la Nutrición. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
Mexico City, 14080, Mexico
-
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Mexico City, Tlalpan, 14080, Mexico