Supercharged immune cells take on tough lymphoma

NCT ID NCT06120166

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase trial tests a new kind of CAR-T cell therapy, called Meta10-19, for people with diffuse large B-cell lymphoma that has come back or not responded to treatment. The cells are 'metabolically armed' to give them extra energy to fight cancer. The study will enroll 18 adults to find the safest dose and see if the treatment shrinks tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Metabolically armed CD19 CAR-T cells (Meta10-19)

What this could lead to

If it works, this could point toward a more effective treatment for hard-to-treat lymphoma by boosting the energy of cancer-fighting immune cells.

What could go wrong

This is a very early, small trial (18 people) testing safety and dosing first. The approach may not work or could cause severe side effects like cytokine release syndrome.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma follicular lymphoma primary mediastinal large B-cell lymphoma relapsed/refractory diffuse large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The first affiliated hospital of medical college of zhejiang university

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact