Gene therapy virus shows promise against tough lung cancer

NCT ID NCT03710876

First seen May 07, 2026 · Last updated May 07, 2026

Summary

This study tested a new treatment for malignant pleural mesothelioma, a rare and serious cancer of the lung lining. It included 53 adults who had already tried at least one other treatment. The approach uses a virus to deliver interferon directly into the chest, combined with two drugs (celecoxib and gemcitabine), to see if it helps people live longer compared to the drugs alone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MALIGNANT PLEURAL MESOTHELIOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Azienda Ospedaliero Universitaria Senese, Cancer Immunotherapy

    Siena, Tuscany, 53100, Italy

  • Beatson, West of Scotland Cancer Centre

    Glasgow, Scotland, G12 0YN, United Kingdom

  • CHRU de Brest - Hopital Augustin Morvan

    Brest, 29200, France

  • CHRU de Lille

    Lille, 59037, France

  • CHU de Caen - Hopital Cote de Nacre

    Caen, 14033, France

  • CHU de Nantes - Hôpital Nord Laennec

    Saint-Herblain, 44093, France

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, France

  • Centrum Onkologii Instytut im. Marii Sklodowskiej - Curie, Klinika Nowotworow Tkanek Miekkich, Kosci i Czerniakow

    Warsaw, ul. Roentgena 5, Poland

  • Chris O'Brien Lifehouse

    Camperdown, New South Wales, 2050, Australia

  • Churchill Hospital

    Oxford, Oxford, OX3 7LJ, United Kingdom

  • Derriford Hospital ; Derriford Hospital

    Plymouth, Devon, PL6 8DH, United Kingdom

  • Evangelisches Krankenhaus Hamm

    Hamm, 59063, Germany

  • Guy's and St. Thomas' NHS Trust

    London, SE1 9RT, United Kingdom

  • H. Lee Moffitt Cancer Center & Research Institute

    Tampa, Florida, 33612, United States

  • Institut Bergonie

    Bordeaux, 33076, France

  • Institut Curie - Oncologie Medicale

    Paris, 75248, France

  • Institut Universitaire de Cardiologie et de Pneumologie De Quebec

    Québec, Sainte-Foy, G1V 4G5, Canada

  • Marlene & Stewart Greenbaum Comprehensive Cancer Center

    Baltimore, Maryland, 21201, United States

  • Masonic Cancer Center - University of Minnesota

    Minneapolis, Minnesota, 55455, United States

  • Med Polonia Sp. z o.o.

    Poznan, 60-693, Poland

  • Monash Medical Centre

    Clayton, Victoria, 3168, Australia

  • Petrov National Medical Research Center of Oncology

    Saint Petersburg, 197758, Russia

  • Royal Marsden Foundation Trust

    Sutton, Surrey, SM2 5PT, United Kingdom

  • Universitatsklinikum Regensburg

    Regensburg, 93053, Germany

  • University of California, Los Angeles (UCLA) - Medical Center

    Los Angeles, California, 90059, United States

  • University of California, San Francisco (UCSF)

    San Francisco, California, 94158, United States

  • University of Maryland Medical Center

    Baltimore, Maryland, 21201, United States

  • University of Pennsylvania Abramson Cancer Center

    Philadelphia, Pennsylvania, 19104, United States

  • Volgograd Regional Clinical Oncology Dispensary

    Volgograd, 404130, Russia

Conditions

Explore the condition pages connected to this study.