New drug targets hidden cause of COPD flare-ups, could replace risky steroids

This study tested whether mepolizumab, a drug that targets specific white blood cells called eosinophils, could help control COPD in patients who have high levels of these cells in their airways. The goal was to see if reducing these cells could decrease severe symptom flare-ups and potentially reduce the need for oral steroids, which have harmful side effects. The trial involved 18 adults with COPD and eosinophilic bronchitis over a 6-month period.