New app aims to ease depression and pain in ankylosing spondylitis patients

NCT ID NCT07647965

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests a WeChat-based program that provides daily mental health check-ins and tailored coping strategies for people with ankylosing spondylitis who also have mild-to-moderate depression or anxiety. Thirty-six adults will be split into two groups: one receives the program (including video CBT sessions and symptom-triggered exercises), while the other gets standard education. The main goal is to see if the program is feasible and acceptable, with early looks at its effects on mood, pain, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Ecological momentary intervention (WeChat-based CBT sessions and symptom-triggered coping modules)
What this could lead to
If it works, this could provide a practical, on-demand mental health tool for people with ankylosing spondylitis, helping them manage pain, anxiety, and depression in real time.
What could go wrong
This is a very small pilot study (36 people) focused on feasibility, not proof of effectiveness. The results may not apply to broader populations, and the app-based approach may not work for everyone.

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Conditions

The condition(s) this trial relates to.

ankylosing spondylitis Psychological Well-Being

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • School of Nursing, The Hong Kong Polytechnic University

    Hong Kong, Hong Kong

  • The Rheumatology outpatient department at the First Affiliated Hospital of Guangzhou University of Chinese Medicine

    Guangzhou, China

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