Promising drug combo could tame debilitating vertigo in Meniere's disease
NCT ID NCT05582837
First seen Apr 16, 2026 · Last updated May 15, 2026 · Updated 2 times
Summary
This study tests whether a stepwise regimen of two medications, nortriptyline and topiramate, can reduce vertigo and other symptoms in people with Meniere's disease. The trial will enroll 40 adults aged 25 to 85 who have active or frequent symptoms. Participants will be randomly assigned to receive the drug combo or a placebo, and researchers will measure changes in quality of life and symptom severity over time.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
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Locations
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University of California, Irvine Medical Center ENT Clinic (Pavilion 2)
RECRUITINGOrange, California, 92868, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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