Supercharged immune cells take on tough lymphoma after transplant

NCT ID NCT02051257

First seen Apr 08, 2026 · Last updated May 07, 2026 · Updated 5 times

Summary

This early-phase trial tests a new approach for people with aggressive B-cell non-Hodgkin lymphoma that has come back after treatment. After a standard stem cell transplant, patients receive their own immune cells (T cells) that have been genetically modified in a lab to better recognize and attack lymphoma cells. The main goal is to find the highest safe dose of these modified cells and see if they can help prevent the cancer from returning.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.