Sleep hormone melatonin tested as painkiller for C-Section moms

NCT ID NCT07380568

Completed Symptom relief Sponsor: Benha University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 15, 2026 · Updated 4 times

Summary

This study tests whether taking melatonin before a planned C-section can lower pain afterward. Sixty women will receive either 5 mg, 10 mg, or a placebo pill one hour before surgery. Researchers will track pain levels, how soon they need extra pain relief, and any side effects over 24 hours.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Melatonin
What this could lead to: If it works, this could offer a simple, low-cost way to reduce pain after C-section and cut down on opioid use.
What could go wrong: This is a small, early-phase trial with only 60 participants. Melatonin may not reduce pain significantly, and side effects like drowsiness or dizziness are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CESAREAN SECTION PAIN PAIN AFTER SURGERY PAIN MANAGEMENT

Contacts and locations

Locations

Benha University Hospital

Banhā, Egypt

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