Could a sleep hormone help heal damaged hearts in new moms?

NCT ID NCT07334197

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding melatonin (a natural sleep hormone) to standard heart failure treatment can improve heart function in women with peripartum cardiomyopathy, a rare heart condition that develops during or after pregnancy. 25 women will receive either melatonin, selenium, or a placebo for 3 months. The goal is to see if these supplements help the heart pump better and reduce inflammation.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Melatonin (10 mg daily) and Selenium (100 mcg daily)
What this could lead to
If it works, this could point toward a simple, low-cost addition to standard heart failure therapy for women with peripartum cardiomyopathy, potentially improving heart recovery.
What could go wrong
This is a very small, early-phase trial with only 25 participants. The results may not apply to all patients, and the benefits of melatonin for heart function are not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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