Melatonin shows promise for perimenopause symptoms in small trial
NCT ID NCT06192641
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether taking 3 mg of melatonin at bedtime for 30 days can ease common perimenopause symptoms like sleep problems, mood changes, and pain. Twenty-four women aged 45 and older with irregular periods participated. The goal is to see if melatonin offers a simple, non-hormonal way to feel better during this transition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- melatonin
- What this could lead to
- If it works, this could point toward a simple, non-hormonal option to ease common perimenopause symptoms like poor sleep, mood changes, and pain.
- What could go wrong
- This is a very small, early-phase trial with only 24 participants. Results may not apply to all women, and melatonin's effects could be mild or no better than placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Gabriela Laste
Lajeado, Rio Grande do Sul, 95900-000, Brazil
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