Personalized mRNA vaccine trial aims to supercharge immune system against skin cancer

NCT ID NCT06961006

Recruiting now Disease control Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding a new personalized cancer vaccine (V940) to standard immunotherapy (pembrolizumab) works better for advanced melanoma that has spread. The goal is to see if this combination helps patients live longer without their cancer getting worse compared to receiving immunotherapy alone. The trial will enroll 160 adults with advanced melanoma who have not yet received treatment for their spread disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Blacktown Hospital ( Site 2001)
RECRUITING

Blacktown, New South Wales, 2148, Australia

Contact Phone: •••-•••-••••
Centre Hospitalier Universitaire de Nice - Hôpital l'Archet-Dermatology Department ( Site 2042)
RECRUITING

Nice, Alpes-Maritimes, 06202, France

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European Interbalkan Medical Center ( Site 2081)
RECRUITING

Thessaloniki, 570 01, Greece

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Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 3021)
RECRUITING

Milan, Milano, 20133, Italy

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Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 3023)
RECRUITING

Roma, 00168, Italy

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Fred Hutchinson Cancer Center ( Site 4041)
RECRUITING

Seattle, Washington, 98109, United States

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General Hospital of Athens "Laiko" ( Site 2080)
RECRUITING

Athens, Attica, 115 27, Greece

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Gustave Roussy ( Site 2040)
RECRUITING

Villejuif, Île-de-France Region, 94800, France

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HaEmek Medical Center ( Site 3003)
RECRUITING

Afula, 1834111, Israel

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Hadassah Medical Center ( Site 3001)
RECRUITING

Jerusalem, 9112001, Israel

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Harbour Cancer & Wellness ( Site 3040)
RECRUITING

Auckland, 1023, New Zealand

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Highlands Oncology Group ( Site 4042)
RECRUITING

Springdale, Arkansas, 72762, United States

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Hospital Clínic Barcelona ( Site 3080)
RECRUITING

Barcelona, 08036, Spain

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Hospital Universitari Vall d'Hebron ( Site 3081)
RECRUITING

Barcelona, 08035, Spain

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Hospital Universitario Ramón y Cajal-Medical Oncology ( Site 3082)
RECRUITING

Madrid, 28034, Spain

Contact Phone: •••-•••-••••
Hôpital Saint-Louis ( Site 2041)
RECRUITING

Paris, Île-de-France Region, 75010, France

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Inova Schar Cancer Institute ( Site 4046)
RECRUITING

Fairfax, Virginia, 22031, United States

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Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 4000)
RECRUITING

Porto, 4200-072, Portugal

Contact Phone: •••-•••-••••
Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 3020)
RECRUITING

Naples, 80131, Italy

Contact Phone: •••-•••-••••
Istituto Oncologico Veneto IRCCS ( Site 3022)
RECRUITING

Padua, 35128, Italy

Contact Phone: •••-•••-••••
John Theurer Cancer Center at Hackensack University Medical Center ( Site 4047)
RECRUITING

Hackensack, New Jersey, 07601, United States

Contact Phone: •••-•••-••••
Melanoma Institute Australia ( Site 2000)
RECRUITING

Wollstonecraft, New South Wales, 2065, Australia

Contact Phone: •••-•••-••••
Metropolitan Hospital ( Site 2082)
RECRUITING

Athens, Attica, 18547, Greece

Contact Phone: •••-•••-••••
NCT ( Site 2065)
RECRUITING

Heidelberg, Baden-Wurttemberg, 69120, Germany

Contact Phone: •••-•••-••••
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 3060)
RECRUITING

Warsaw, Masovian Voivodeship, 02-781, Poland

Contact Phone: •••-•••-••••
One Clinical Research ( Site 2002)
RECRUITING

Nedlands, Western Australia, 6009, Australia

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Rabin Medical Center ( Site 3002)
RECRUITING

Petah Tikva, 4941492, Israel

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Sheba Medical Center ( Site 3000)
RECRUITING

Ramat Gan, 5265601, Israel

Contact Phone: •••-•••-••••
Sunnybrook Research Institute ( Site 2022)
RECRUITING

Toronto, Ontario, M4N 3M5, Canada

Contact Phone: •••-•••-••••
UCSF Medical Center at Mission Bay ( Site 4044)
RECRUITING

San Francisco, California, 94158, United States

Contact Phone: •••-•••-••••
Unidade Local de Saude Lisboa Ocidental - Hospital de São Francisco Xavier ( Site 4002)
RECRUITING

Lisbon, Lisbon District, 1449-005, Portugal

Contact Phone: •••-•••-••••
Unidade Local de Saude de Santa Maria - Hospital de Santa Maria ( Site 4001)
RECRUITING

Lisbon, 1649-035, Portugal

Contact Phone: •••-•••-••••
Universitaetsklinikum Essen ( Site 2061)
RECRUITING

Essen, North Rhine-Westphalia, 45147, Germany

Contact Phone: •••-•••-••••
Universitaetsklinikum Hamburg-Eppendorf ( Site 2060)
RECRUITING

Hamburg, 20251, Germany

Contact Phone: •••-•••-••••
Universitaetsklinikum Koeln ( Site 2064)
RECRUITING

Cologne, North Rhine-Westphalia, 50937, Germany

Contact Phone: •••-•••-••••
Universitätsklinikum Frankfurt Goethe-Universität ( Site 2063)
RECRUITING

Frankfurt am Main, Hesse, 60590, Germany

Contact Phone: •••-•••-••••
Uniwersytecki Szpital Kliniczny w Poznaniu ( Site 3061)
RECRUITING

Poznan, Greater Poland Voivodeship, 50 659, Poland

Contact Phone: •••-•••-••••
William Osler Health System (Brampton Civic Hospital) ( Site 2023)
RECRUITING

Brampton, Ontario, L6R 3J7, Canada

Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

MALIGNANT MELANOMA