Boosting the immune system to fight skin cancer before surgery

NCT ID NCT04708418

Ongoing Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study is testing if a new drug combination works better than a standard drug alone to shrink melanoma tumors before surgery. It involves 60 adults with stage III melanoma that can be surgically removed. The goal is to see if the combination helps the immune system attack the cancer more effectively and reduces the chance of the cancer returning.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Alaska Breast Care and Surgery LLC

Anchorage, Alaska, 99508, United States
Alaska Oncology and Hematology LLC

Anchorage, Alaska, 99508, United States
Alaska Women's Cancer Care

Anchorage, Alaska, 99508, United States
Alta Bates Summit Medical Center - Summit Campus

Oakland, California, 94609, United States
Anchorage Associates in Radiation Medicine

Anchorage, Alaska, 98508, United States
Anchorage Oncology Centre

Anchorage, Alaska, 99508, United States
Armes Family Cancer Center

Findlay, Ohio, 45840, United States
Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066, United States
Avera Cancer Institute

Sioux Falls, South Dakota, 57105, United States
Avera Cancer Institute-Aberdeen

Aberdeen, South Dakota, 57401, United States
BJC Outpatient Center at Sunset Hills

Sunset Hills, Missouri, 63127, United States
Banner North Colorado Medical Center

Greeley, Colorado, 80631, United States
Banner North Colorado Medical Center - Loveland Campus

Loveland, Colorado, 80539, United States
Banner University Medical Center - Tucson

Tucson, Arizona, 85719, United States
Bay Area Breast Surgeons Inc

Emeryville, California, 94608, United States
Bay Area Hospital

Coos Bay, Oregon, 97420, United States
Bay Area Tumor Institute

Oakland, California, 94609, United States
Beacon Kalamazoo

Kalamazoo, Michigan, 49048, United States
Beacon Kalamazoo Cancer Center

Kalamazoo, Michigan, 49009, United States
Blanchard Valley Hospital

Findlay, Ohio, 45840, United States
Bronson Battle Creek

Battle Creek, Michigan, 49017, United States
Bronson Methodist Hospital

Kalamazoo, Michigan, 49007, United States
Cancer Care Center of O'Fallon

O'Fallon, Illinois, 62269, United States
Cancer Care Specialists of Illinois - Decatur

Decatur, Illinois, 62526, United States
Cancer and Hematology Centers of Western Michigan - Norton Shores

Norton Shores, Michigan, 49444, United States
Central Care Cancer Center - Bolivar

Bolivar, Missouri, 65613, United States
Central Care Cancer Center - Garden City

Garden City, Kansas, 67846, United States
Central Care Cancer Center - Great Bend

Great Bend, Kansas, 67530, United States
Central Vermont Medical Center/National Life Cancer Treatment

Berlin Corners, Vermont, 05602, United States
Centralia Oncology Clinic

Centralia, Illinois, 62801, United States
Clackamas Radiation Oncology Center

Clackamas, Oregon, 97015, United States
Contra Costa Regional Medical Center

Martinez, California, 94553-3156, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital

Grand Rapids, Michigan, 49503, United States
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital

Grand Rapids, Michigan, 49503, United States
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center

Saint Joseph, Michigan, 49085, United States
Corewell Health Lakeland Hospitals - Niles Hospital

Niles, Michigan, 49120, United States
Corewell Health Lakeland Hospitals - Saint Joseph Hospital

Saint Joseph, Michigan, 49085, United States
Corewell Health Reed City Hospital

Reed City, Michigan, 49677, United States
CoxHealth South Hospital

Springfield, Missouri, 65807, United States
Crossroads Cancer Center

Effingham, Illinois, 62401, United States
Dayton Physician LLC - Englewood

Dayton, Ohio, 45415, United States
Dayton Physicians LLC - Troy

Troy, Ohio, 45373, United States
Dayton Physicians LLC-Atrium

Franklin, Ohio, 45005, United States
Dayton Physicians LLC-Miami Valley South

Centerville, Ohio, 45459, United States
Dayton Physicians LLC-Wayne

Greenville, Ohio, 45331, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Epic Care Cyberknife Center

Walnut Creek, California, 94597, United States
Epic Care Partners in Cancer Care

Emeryville, California, 94608, United States
Epic Care-Dublin

Dublin, California, 94568, United States
Fairbanks Memorial Hospital

Fairbanks, Alaska, 99701, United States
Freeman Health System

Joplin, Missouri, 64804, United States
Greater Dayton Cancer Center

Kettering, Ohio, 45409, United States
Guthrie Medical Group PC-Robert Packer Hospital

Sayre, Pennsylvania, 18840, United States
Heartland Regional Medical Center

Saint Joseph, Missouri, 64506, United States
Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States
Illinois CancerCare - Washington

Washington, Illinois, 61571, United States
Illinois CancerCare-Bloomington

Bloomington, Illinois, 61704, United States
Illinois CancerCare-Canton

Canton, Illinois, 61520, United States
Illinois CancerCare-Carthage

Carthage, Illinois, 62321, United States
Illinois CancerCare-Dixon

Dixon, Illinois, 61021, United States
Illinois CancerCare-Eureka

Eureka, Illinois, 61530, United States
Illinois CancerCare-Galesburg

Galesburg, Illinois, 61401, United States
Illinois CancerCare-Kewanee Clinic

Kewanee, Illinois, 61443, United States
Illinois CancerCare-Macomb

Macomb, Illinois, 61455, United States
Illinois CancerCare-Ottawa Clinic

Ottawa, Illinois, 61350, United States
Illinois CancerCare-Pekin

Pekin, Illinois, 61554, United States
Illinois CancerCare-Peoria

Peoria, Illinois, 61615, United States
Illinois CancerCare-Peru

Peru, Illinois, 61354, United States
Illinois CancerCare-Princeton

Princeton, Illinois, 61356, United States
Indu and Raj Soin Medical Center

Beavercreek, Ohio, 45431, United States
Jefferson Healthcare

Port Townsend, Washington, 98368, United States
Kadlec Clinic Hematology and Oncology

Kennewick, Washington, 99336, United States
Katmai Oncology Group

Anchorage, Alaska, 99508, United States
Kettering Medical Center

Kettering, Ohio, 45429, United States
Louisiana Hematology Oncology Associates LLC

Baton Rouge, Louisiana, 70809, United States
MU Health Care Goldschmidt Cancer Center

Jefferson City, Missouri, 65109, United States
Marshfield Medical Center - Minocqua

Minocqua, Wisconsin, 54548, United States
Marshfield Medical Center - Weston

Weston, Wisconsin, 54476, United States
Marshfield Medical Center-EC Cancer Center

Eau Claire, Wisconsin, 54701, United States
Marshfield Medical Center-Marshfield

Marshfield, Wisconsin, 54449, United States
Marshfield Medical Center-Rice Lake

Rice Lake, Wisconsin, 54868, United States
Marshfield Medical Center-River Region at Stevens Point

Stevens Point, Wisconsin, 54482, United States
Mary Bird Perkins Cancer Center

Baton Rouge, Louisiana, 70809, United States
Mary Greeley Medical Center

Ames, Iowa, 50010, United States
McFarland Clinic - Ames

Ames, Iowa, 50010, United States
McFarland Clinic - Boone

Boone, Iowa, 50036, United States
McFarland Clinic - Jefferson

Jefferson, Iowa, 50129, United States
McFarland Clinic - Marshalltown

Marshalltown, Iowa, 50158, United States
McFarland Clinic - Trinity Cancer Center

Fort Dodge, Iowa, 50501, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Memorial Hospital of Carbondale

Carbondale, Illinois, 62902, United States
Mercy Cancer Center - Cape Girardeau

Cape Girardeau, Missouri, 63703, United States
Mercy Clinic-Rolla-Cancer and Hematology

Rolla, Missouri, 65401, United States
Mercy Hospital Fort Smith

Fort Smith, Arkansas, 72903, United States
Mercy Hospital Joplin

Joplin, Missouri, 64804, United States
Mercy Hospital Oklahoma City

Oklahoma City, Oklahoma, 73120, United States
Mercy Hospital Saint Louis

St Louis, Missouri, 63141, United States
Mercy Hospital South

St Louis, Missouri, 63128, United States
Mercy Hospital Springfield

Springfield, Missouri, 65804, United States
Mercy Oncology and Hematology - Clayton-Clarkson

Ballwin, Missouri, 63011, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61636, United States
Miami Valley Hospital

Dayton, Ohio, 45409, United States
Miami Valley Hospital North

Dayton, Ohio, 45415, United States
Miami Valley Hospital South

Centerville, Ohio, 45459, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
Missouri Baptist Sullivan Hospital

Sullivan, Missouri, 63080, United States
Mountain Blue Cancer Care Center - Swedish

Englewood, Colorado, 80113, United States
Munson Medical Center

Traverse City, Michigan, 49684, United States
Oncology Hematology Care Inc-Kenwood

Cincinnati, Ohio, 45236, United States
Orion Cancer Care

Findlay, Ohio, 45840, United States
Parkland Health Center - Farmington

Farmington, Missouri, 63640, United States
PeaceHealth Saint John Medical Center

Longview, Washington, 98632, United States
PeaceHealth Saint Joseph Medical Center

Bellingham, Washington, 98225, United States
PeaceHealth Southwest Medical Center

Vancouver, Washington, 98664, United States
PeaceHealth United General Medical Center

Sedro-Woolley, Washington, 98284, United States
Phelps Health Delbert Day Cancer Institute

Rolla, Missouri, 65401, United States
Presbyterian - Saint Lukes Medical Center - Health One

Denver, Colorado, 80218, United States
Providence Alaska Medical Center

Anchorage, Alaska, 99508, United States
Providence Cancer Institute Clackamas Clinic

Clackamas, Oregon, 97015, United States
Providence Newberg Medical Center

Newberg, Oregon, 97132, United States
Providence Portland Medical Center

Portland, Oregon, 97213, United States
Providence Regional Cancer Partnership

Everett, Washington, 98201, United States
Providence Regional Cancer System-Aberdeen

Aberdeen, Washington, 98520, United States
Providence Regional Cancer System-Centralia

Centralia, Washington, 98531, United States
Providence Regional Cancer System-Lacey

Lacey, Washington, 98503, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center

Burbank, California, 91505, United States
Providence Saint Mary Regional Cancer Center

Walla Walla, Washington, 99362, United States
Providence Saint Vincent Medical Center

Portland, Oregon, 97225, United States
Reid Health

Richmond, Indiana, 47374, United States
Rocky Mountain Cancer Centers - Centennial

Centennial, Colorado, 80112, United States
Rocky Mountain Cancer Centers - Swedish

Englewood, Colorado, 80113, United States
Rocky Mountain Cancer Centers-Aurora

Aurora, Colorado, 80012, United States
Rocky Mountain Cancer Centers-Boulder

Boulder, Colorado, 80304, United States
Rocky Mountain Cancer Centers-Littleton

Littleton, Colorado, 80120, United States
Rocky Mountain Cancer Centers-Midtown

Denver, Colorado, 80218, United States
Rocky Mountain Cancer Centers-Rose

Denver, Colorado, 80220, United States
Rocky Mountain Cancer Centers-Sky Ridge

Lone Tree, Colorado, 80124, United States
Rocky Mountain Cancer Centers-Thornton

Thornton, Colorado, 80260, United States
SIH Cancer Institute

Carterville, Illinois, 62918, United States
SSM Health Good Samaritan

Mount Vernon, Illinois, 62864, United States
Saint Charles Health System

Bend, Oregon, 97701, United States
Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States
Saint Joseph Hospital - Orange

Orange, California, 92868, United States
Saint Luke's Cancer Center - Allentown

Allentown, Pennsylvania, 18104, United States
Saint Luke's Cancer Institute - Boise

Boise, Idaho, 83712, United States
Saint Luke's Cancer Institute - Fruitland

Fruitland, Idaho, 83619, United States
Saint Luke's Cancer Institute - Meridian

Meridian, Idaho, 83642, United States
Saint Luke's Cancer Institute - Nampa

Nampa, Idaho, 83687, United States
Saint Luke's Cancer Institute - Twin Falls

Twin Falls, Idaho, 83301, United States
Saint Luke's Hospital-Anderson Campus

Easton, Pennsylvania, 18045, United States
Saint Luke's Hospital-Quakertown Campus

Quakertown, Pennsylvania, 18951, United States
Saint Luke's University Hospital-Bethlehem Campus

Bethlehem, Pennsylvania, 18015, United States
Saint Patrick Hospital - Community Hospital

Missoula, Montana, 59802, United States
Sainte Genevieve County Memorial Hospital

Sainte Genevieve, Missouri, 63670, United States
Sky Ridge Medical Center

Lone Tree, Colorado, 80124, United States
Southern Illinois University School of Medicine

Springfield, Illinois, 62702, United States
Springfield Clinic

Springfield, Illinois, 62702, United States
Springfield Memorial Hospital

Springfield, Illinois, 62781, United States
Springfield Regional Cancer Center

Springfield, Ohio, 45504, United States
Springfield Regional Medical Center

Springfield, Ohio, 45504, United States
Swedish Cancer Institute-Edmonds

Edmonds, Washington, 98026, United States
Swedish Cancer Institute-Issaquah

Issaquah, Washington, 98029, United States
Swedish Medical Center

Englewood, Colorado, 80113, United States
Swedish Medical Center-Ballard Campus

Seattle, Washington, 98107, United States
Swedish Medical Center-First Hill

Seattle, Washington, 98122, United States
Terrebonne General Medical Center

Houma, Louisiana, 70360, United States
The Medical Center of Aurora

Aurora, Colorado, 80012, United States
The Melanoma and Skin Cancer Institute

Englewood, Colorado, 80113, United States
Trinity Health Grand Rapids Hospital

Grand Rapids, Michigan, 49503, United States
Trinity Health Muskegon Hospital

Muskegon, Michigan, 49444, United States
UC Irvine Health/Chao Family Comprehensive Cancer Center

Orange, California, 92868, United States
UM Sylvester Comprehensive Cancer Center at Aventura

Aventura, Florida, 33180, United States
UM Sylvester Comprehensive Cancer Center at Coral Gables

Coral Gables, Florida, 33146, United States
UM Sylvester Comprehensive Cancer Center at Deerfield Beach

Deerfield Beach, Florida, 33442, United States
UM Sylvester Comprehensive Cancer Center at Plantation

Plantation, Florida, 33324, United States
University of Arizona Cancer Center-North Campus

Tucson, Arizona, 85719, United States
University of Illinois

Chicago, Illinois, 60612, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center

Miami, Florida, 33136, United States
University of Michigan Health - West

Wyoming, Michigan, 49519, United States
University of Pittsburgh Cancer Institute (UPCI)

Pittsburgh, Pennsylvania, 15232, United States
University of Vermont Medical Center

Burlington, Vermont, 05401, United States
University of Virginia Cancer Center

Charlottesville, Virginia, 22908, United States
Upper Valley Medical Center

Troy, Ohio, 45373, United States
VCU Massey Comprehensive Cancer Center

Richmond, Virginia, 23298, United States
Valley Radiation Oncology

Peru, Illinois, 61354, United States
Wayne Hospital

Greenville, Ohio, 45331, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
Western Illinois Cancer Treatment Center

Galesburg, Illinois, 61401, United States

Conditions

Explore the condition pages connected to this study.

CLINICAL STAGE III CUTANEOUS MELANOMA AJCC V8 MELANOMA OF UNKNOWN PRIMARY PATHOLOGIC STAGE IIIB CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IIID CUTANEOUS MELANOMA AJCC V8 RECURRENT CUTANEOUS MELANOMA