Immune cell army plus drug shows promise against tough melanoma

NCT ID NCT05176470

First seen Feb 25, 2026 · Last updated May 12, 2026 · Updated 7 times

Summary

This early-stage trial tests a two-pronged attack on advanced melanoma. First, doctors remove some of the patient's own immune cells from a tumor, grow them into a larger army in a lab (Lifileucel), and put them back. Second, they give the drug pembrolizumab to help those cells work better. The goal is to see if this combination is safe and can shrink tumors in people with stage IIIB-D or IV melanoma.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.