Polio virus weaponized to fight tough melanoma
NCT ID NCT04577807
Summary
This study tested a new treatment called lerapolturev, which is a modified polio virus, for people with advanced skin melanoma. The cancer in these patients had stopped responding to standard immunotherapy drugs (anti-PD-1). Researchers wanted to see if injecting the virus directly into tumors, either alone or combined with another immunotherapy, could help control the cancer. The main goals were to see if tumors shrank and to check the safety of this approach.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MELANOMA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Cancer Treatment Centers of America
Zion, Illinois, 60099, United States
-
Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
-
Henry Ford Health System
Detroit, Michigan, 48208, United States
-
HonorHealth Research Institute
Scottsdale, Arizona, 85258, United States
-
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
-
Orlando Health U7 Health Cancer Center
Orlando, Florida, 32806, United States
-
Rush University Medical Center
Chicago, Illinois, 60612, United States
-
Texas Oncology -Baylor Charles A. Sammons Cancer Center
Dallas, Texas, 75246, United States
-
University of Pittsburgh Hillman Cancer Center
Pittsburgh, Pennsylvania, 15213, United States
-
Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
-
Virginia Commonwealth University
Richmond, Virginia, 23298, United States
-
West Virginia University Medical Center
Morgantown, West Virginia, 26506, United States
Conditions
Explore the condition pages connected to this study.