Two-Drug combo tested in fight against advanced skin cancer

NCT ID NCT01708941

Ongoing Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study tested whether adding high-dose interferon to the immunotherapy drug ipilimumab helps control advanced melanoma better than ipilimumab alone. It also compared two different doses of ipilimumab. The trial involved 88 adults with stage III or IV melanoma that couldn't be removed by surgery, aiming to see which approach keeps the cancer from progressing longer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for STAGE IV CUTANEOUS MELANOMA AJCC V6 AND V7 are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

AMG Libertyville - Oncology

Libertyville, Illinois, 60048, United States
Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Adena Regional Medical Center

Chillicothe, Ohio, 45601, United States
AdventHealth Littleton

Littleton, Colorado, 80122, United States
AdventHealth Parker

Parker, Colorado, 80138, United States
AdventHealth Porter

Denver, Colorado, 80210, United States
Alegent Health Bergan Mercy Medical Center

Omaha, Nebraska, 68124, United States
Alegent Health Immanuel Medical Center

Omaha, Nebraska, 68122, United States
Alegent Health Lakeside Hospital

Omaha, Nebraska, 68130, United States
Allegiance Health

Jackson, Michigan, 49201, United States
Ascension Southeast Wisconsin Hospital - Saint Joseph Campus

Milwaukee, Wisconsin, 53210, United States
Ascension Via Christi Hospitals Wichita

Wichita, Kansas, 67214, United States
Associates In Womens Health

Wichita, Kansas, 67208, United States
Aurora Bay Area Medical Group-Marinette

Marinette, Wisconsin, 54143, United States
Aurora BayCare Medical Center

Green Bay, Wisconsin, 54311, United States
Aurora Cancer Care-Grafton

Grafton, Wisconsin, 53024, United States
Aurora Cancer Care-Kenosha South

Kenosha, Wisconsin, 53142, United States
Aurora Cancer Care-Milwaukee

Milwaukee, Wisconsin, 53209, United States
Aurora Cancer Care-Milwaukee West

Wauwatosa, Wisconsin, 53226, United States
Aurora Cancer Care-Racine

Racine, Wisconsin, 53406, United States
Aurora Cancer Care-Southern Lakes VLCC

Burlington, Wisconsin, 53105, United States
Aurora Cancer Care-Waukesha

Waukesha, Wisconsin, 53188, United States
Aurora Health Care Germantown Health Center

Germantown, Wisconsin, 53022, United States
Aurora Health Center-Fond du Lac

Fond du Lac, Wisconsin, 54937, United States
Aurora Medical Center in Summit

Summit, Wisconsin, 53066, United States
Aurora Saint Luke's Medical Center

Milwaukee, Wisconsin, 53215, United States
Aurora Sinai Medical Center

Milwaukee, Wisconsin, 53233, United States
Aurora West Allis Medical Center

West Allis, Wisconsin, 53227, United States
BJC Outpatient Center at Sunset Hills

Sunset Hills, Missouri, 63127, United States
Banner North Colorado Medical Center

Greeley, Colorado, 80631, United States
Banner North Colorado Medical Center - Loveland Campus

Loveland, Colorado, 80539, United States
Bay Area Medical Center

Marinette, Wisconsin, 54143, United States
Beebe Health Campus

Rehoboth Beach, Delaware, 19971, United States
Beebe Medical Center

Lewes, Delaware, 19958, United States
Bixby Medical Center

Adrian, Michigan, 49221, United States
Boulder Community Foothills Hospital

Boulder, Colorado, 80303, United States
Cancer Care Center of O'Fallon

O'Fallon, Illinois, 62269, United States
Cancer Care Specialists of Illinois - Decatur

Decatur, Illinois, 62526, United States
Cancer Center of Kansas - Chanute

Chanute, Kansas, 66720, United States
Cancer Center of Kansas - Dodge City

Dodge City, Kansas, 67801, United States
Cancer Center of Kansas - El Dorado

El Dorado, Kansas, 67042, United States
Cancer Center of Kansas - Fort Scott

Fort Scott, Kansas, 66701, United States
Cancer Center of Kansas - McPherson

McPherson, Kansas, 67460, United States
Cancer Center of Kansas - Newton

Newton, Kansas, 67114, United States
Cancer Center of Kansas - Parsons

Parsons, Kansas, 67357, United States
Cancer Center of Kansas - Pratt

Pratt, Kansas, 67124, United States
Cancer Center of Kansas - Salina

Salina, Kansas, 67401, United States
Cancer Center of Kansas - Wellington

Wellington, Kansas, 67152, United States
Cancer Center of Kansas - Wichita

Wichita, Kansas, 67214, United States
Cancer Center of Kansas - Winfield

Winfield, Kansas, 67156, United States
Cancer Center of Kansas-Independence

Independence, Kansas, 67301, United States
Cancer Center of Kansas-Kingman

Kingman, Kansas, 67068, United States
Cancer Center of Kansas-Liberal

Liberal, Kansas, 67905, United States
Cancer Center of Kansas-Manhattan

Manhattan, Kansas, 66502, United States
Cancer Center of Kansas-Wichita Medical Arts Tower

Wichita, Kansas, 67208, United States
Cancer Center of Western Wisconsin

New Richmond, Wisconsin, 54017, United States
Cancer Partners of Nebraska

Lincoln, Nebraska, 68516, United States
Carle Cancer Center

Urbana, Illinois, 61801, United States
Carle Cancer Institute Normal

Normal, Illinois, 61761, United States
Carle Physician Group-Effingham

Effingham, Illinois, 62401, United States
Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, 61938, United States
Carle at The Riverfront

Danville, Illinois, 61832, United States
Central Illinois Hematology Oncology Center

Springfield, Illinois, 62702, United States
Centralia Oncology Clinic

Centralia, Illinois, 62801, United States
Christiana Care - Union Hospital

Elkton, Maryland, 21921, United States
Christiana Care Health System-Christiana Hospital

Newark, Delaware, 19718, United States
Christiana Care Health System-Wilmington Hospital

Wilmington, Delaware, 19801, United States
Colorado Blood Cancer Institute

Denver, Colorado, 80218, United States
Columbus NCI Community Oncology Research Program

Columbus, Ohio, 43215, United States
Columbus Oncology and Hematology Associates Inc

Columbus, Ohio, 43214, United States
Constantinou, Costas L MD (UIA Investigator)

Bettendorf, Iowa, 52722, United States
Cooper Hospital University Medical Center

Camden, New Jersey, 08103, United States
Corewell Health Dearborn Hospital

Dearborn, Michigan, 48124, United States
Creighton University Medical Center

Omaha, Nebraska, 68131, United States
Crossroads Cancer Center

Effingham, Illinois, 62401, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Delaware Clinical and Laboratory Physicians PA

Newark, Delaware, 19713, United States
Delaware Health Center-Grady Cancer Center

Delaware, Ohio, 43015, United States
Delaware Radiation Oncology

Delaware, Ohio, 43015, United States
Doctors Hospital

Columbus, Ohio, 43228, United States
Erlanger Medical Center

Chattanooga, Tennessee, 37403, United States
Fairfield Medical Center

Lancaster, Ohio, 43130, United States
Fairview Ridges Hospital

Burnsville, Minnesota, 55337, United States
Fairview Southdale Hospital

Edina, Minnesota, 55435, United States
Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States
Franciscan Saint Anthony Health-Michigan City

Michigan City, Indiana, 46360, United States
Fredericksburg Oncology Inc

Fredericksburg, Virginia, 22401, United States
Fulton County Health Center

Wauseon, Ohio, 43567, United States
Garneau, Stewart C MD (UIA Investigator)

Moline, Illinois, 61265, United States
Geisinger Cancer Services-Pottsville

Pottsville, Pennsylvania, 17901, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822, United States
Geisinger Medical Center-Cancer Center Hazleton

Hazleton, Pennsylvania, 18201, United States
Geisinger Medical Group

State College, Pennsylvania, 16801, United States
Geisinger Medical Oncology-Lewisburg

Lewisburg, Pennsylvania, 17837, United States
Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, 18711, United States
Genesis Healthcare System Cancer Care Center

Zanesville, Ohio, 43701, United States
Genesys Hurley Cancer Institute

Flint, Michigan, 48503, United States
Grady Memorial Hospital

Delaware, Ohio, 43015, United States
Grant Medical Center

Columbus, Ohio, 43215, United States
Greater Baltimore Medical Center

Baltimore, Maryland, 21204, United States
Green Bay Oncology at Saint Vincent Hospital

Green Bay, Wisconsin, 54301-3526, United States
Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601, United States
HSHS Saint Nicholas Hospital

Sheboygan, Wisconsin, 53081, United States
Health Partners Inc

Minneapolis, Minnesota, 55454, United States
Heartland Cancer Research NCORP

Decatur, Illinois, 62526, United States
Helen F Graham Cancer Center

Newark, Delaware, 19713, United States
Hematology Oncology Associates of Illinois - Skokie

Skokie, Illinois, 60076, United States
Hematology Oncology Associates of Illinois-Highland Park

Highland Park, Illinois, 60035, United States
Hennepin County Medical Center

Minneapolis, Minnesota, 55415, United States
Henry Ford Health Saint John Hospital

Detroit, Michigan, 48236, United States
Hickman Cancer Center

Adrian, Michigan, 49221, United States
Holy Family Memorial Hospital

Manitowoc, Wisconsin, 54221, United States
Hunterdon Medical Center

Flemington, New Jersey, 08822, United States
Hurley Medical Center

Flint, Michigan, 48503, United States
Hutchinson Area Health Care

Hutchinson, Minnesota, 55350, United States
IU Health Central Indiana Cancer Centers-East

Indianapolis, Indiana, 46219, United States
Illinois Cancer Specialists-Niles

Niles, Illinois, 60714, United States
Illinois CancerCare-Bloomington

Bloomington, Illinois, 61704, United States
Illinois CancerCare-Canton

Canton, Illinois, 61520, United States
Illinois CancerCare-Carthage

Carthage, Illinois, 62321, United States
Illinois CancerCare-Eureka

Eureka, Illinois, 61530, United States
Illinois CancerCare-Galesburg

Galesburg, Illinois, 61401, United States
Illinois CancerCare-Macomb

Macomb, Illinois, 61455, United States
Illinois CancerCare-Monmouth

Monmouth, Illinois, 61462, United States
Illinois CancerCare-Ottawa Clinic

Ottawa, Illinois, 61350, United States
Illinois CancerCare-Pekin

Pekin, Illinois, 61554, United States
Illinois CancerCare-Peoria

Peoria, Illinois, 61615, United States
Illinois CancerCare-Peru

Peru, Illinois, 61354, United States
Ingalls Memorial Hospital

Harvey, Illinois, 60426, United States
Intermountain Health Lutheran Hospital

Wheat Ridge, Colorado, 80401, United States
Iowa Lutheran Hospital

Des Moines, Iowa, 50316, United States
Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
Iowa-Wide Oncology Research Coalition NCORP

Des Moines, Iowa, 50309, United States
Knox Community Hospital

Mount Vernon, Ohio, 43050, United States
Lake Huron Medical Center

Port Huron, Michigan, 48060, United States
Lakeview Hospital

Stillwater, Minnesota, 55082, United States
Lancaster Radiation Oncology

Lancaster, Ohio, 43130, United States
Lawrence Memorial Hospital

Lawrence, Kansas, 66044, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Savannah, Georgia, 31405, United States
Lewistown Hospital

Lewistown, Pennsylvania, 17044, United States
Licking Memorial Hospital

Newark, Ohio, 43055, United States
Lima Memorial Hospital

Lima, Ohio, 45804, United States
Longmont United Hospital

Longmont, Colorado, 80501, United States
MU Health Care Goldschmidt Cancer Center

Jefferson City, Missouri, 65109, United States
Marietta Memorial Hospital

Marietta, Ohio, 45750, United States
Mary Greeley Medical Center

Ames, Iowa, 50010, United States
McFarland Clinic - Ames

Ames, Iowa, 50010, United States
McFarland Clinic - Boone

Boone, Iowa, 50036, United States
McFarland Clinic - Jefferson

Jefferson, Iowa, 50129, United States
McFarland Clinic - Marshalltown

Marshalltown, Iowa, 50158, United States
McFarland Clinic - Trinity Cancer Center

Fort Dodge, Iowa, 50501, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Medical Oncology Hematology Consultants PA

Newark, Delaware, 19713, United States
Mercy Cancer Center - Cape Girardeau

Cape Girardeau, Missouri, 63703, United States
Mercy Health - Saint Anne Hospital

Toledo, Ohio, 43623, United States
Mercy Health - Saint Vincent Hospital

Toledo, Ohio, 43608, United States
Mercy Hospital

Coon Rapids, Minnesota, 55433, United States
Mercy Hospital of Tiffin

Tiffin, Ohio, 44883, United States
Mercy Medical Center-Sioux City

Sioux City, Iowa, 51102, United States
Mercy Memorial Hospital

Monroe, Michigan, 48162, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61636, United States
Methodist West Hospital

West Des Moines, Iowa, 50266-7700, United States
Metro Minnesota Community Oncology Research Consortium

Saint Louis Park, Minnesota, 55416, United States
MetroHealth Medical Center

Cleveland, Ohio, 44109, United States
Michigan Cancer Research Consortium NCORP

Ann Arbor, Michigan, 48106, United States
Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109, United States
Minnesota Oncology Hematology PA-Woodbury

Woodbury, Minnesota, 55125, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
Missouri Baptist Sullivan Hospital

Sullivan, Missouri, 63080, United States
Missouri Valley Cancer Consortium

Omaha, Nebraska, 68106, United States
Mount Carmel Health Center West

Columbus, Ohio, 43222, United States
Mountain Blue Cancer Care Center - Swedish

Englewood, Colorado, 80113, United States
MyMichigan Medical Center Saginaw

Saginaw, Michigan, 48601, United States
Natalie Warren Bryant Cancer Center at Saint Francis

Tulsa, Oklahoma, 74136, United States
Nebraska Cancer Research Center

Lincoln, Nebraska, 68510, United States
Nebraska Cancer Specialists - Omaha

Omaha, Nebraska, 68124, United States
Nebraska Hematology and Oncology

Lincoln, Nebraska, 68506, United States
New Ulm Medical Center

New Ulm, Minnesota, 56073, United States
New York Oncology Hematology PC - Albany Medical Center

Albany, New York, 12208, United States
Newark Radiation Oncology

Newark, Ohio, 43055, United States
North Memorial Medical Health Center

Robbinsdale, Minnesota, 55422, United States
Northwestern University

Chicago, Illinois, 60611, United States
OSF Saint Francis Hospital and Medical Group

Escanaba, Michigan, 49829, United States
OSF Saint Francis Medical Center

Peoria, Illinois, 61637, United States
OSF Saint Francis Radiation Oncology at Pekin

Pekin, Illinois, 61554, United States
OSF Saint Francis Radiation Oncology at Peoria Cancer Center

Peoria, Illinois, 61615, United States
OSF Saint Joseph Medical Center

Bloomington, Illinois, 61701, United States
Ochsner Baptist Medical Center

New Orleans, Louisiana, 70115, United States
Ochsner Health Center-Summa

Baton Rouge, Louisiana, 70809, United States
Ochsner Medical Center Jefferson

New Orleans, Louisiana, 70121, United States
Oncology Hematology West PC

Omaha, Nebraska, 68130, United States
Ottawa Regional Hospital and Healthcare Center

Ottawa, Illinois, 61350, United States
Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416, United States
Parkland Health Center-Bonne Terre

Bonne Terre, Missouri, 63628, United States
Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907, United States
Porubcin, Michael MD (UIA Investigator)

Moline, Illinois, 61265, United States
Presbyterian - Saint Lukes Medical Center - Health One

Denver, Colorado, 80218, United States
ProMedica Flower Hospital

Sylvania, Ohio, 43560, United States
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital

Toledo, Ohio, 43606, United States
Proctor Hospital

Peoria, Illinois, 61614, United States
Regional West Medical Center Cancer Center

Scottsbluff, Nebraska, 69361, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Rice Memorial Hospital

Willmar, Minnesota, 56201, United States
Ridgeview Medical Center

Waconia, Minnesota, 55387, United States
Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Rocky Mountain Cancer Centers-Aurora

Aurora, Colorado, 80012, United States
Rocky Mountain Cancer Centers-Boulder

Boulder, Colorado, 80304, United States
Rocky Mountain Cancer Centers-Littleton

Littleton, Colorado, 80120, United States
Rocky Mountain Cancer Centers-Parker

Parker, Colorado, 80138, United States
Rocky Mountain Cancer Centers-Penrose

Colorado Springs, Colorado, 80907, United States
Rose Medical Center

Denver, Colorado, 80220, United States
Rush-Copley Healthcare Center

Yorkville, Illinois, 60560, United States
Rush-Copley Medical Center

Aurora, Illinois, 60504, United States
Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903, United States
Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706, United States
Saint Ann's Hospital

Westerville, Ohio, 43081, United States
Saint Anthony Hospital

Lakewood, Colorado, 80228, United States
Saint Charles Hospital

Oregon, Ohio, 43616, United States
Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States
Saint Francis Regional Medical Center

Shakopee, Minnesota, 55379, United States
Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109, United States
Saint Joseph Hospital - Cancer Centers of Colorado

Denver, Colorado, 80218, United States
Saint Luke's Regional Medical Center

Sioux City, Iowa, 51104, United States
Saint Mary Corwin Medical Center

Pueblo, Colorado, 81004, United States
Saint Vincent Hospital Cancer Center Green Bay

Green Bay, Wisconsin, 54301, United States
Saint Vincent Hospital Cancer Center at Oconto Falls

Oconto Falls, Wisconsin, 54154, United States
Saint Vincent Hospital Cancer Center at Saint Mary's

Green Bay, Wisconsin, 54303, United States
Sainte Genevieve County Memorial Hospital

Sainte Genevieve, Missouri, 63670, United States
Siouxland Regional Cancer Center

Sioux City, Iowa, 51101, United States
Sky Ridge Medical Center

Lone Tree, Colorado, 80124, United States
Smilow Cancer Hospital Care Center at Saint Francis

Hartford, Connecticut, 06105, United States
Southern Illinois University School of Medicine

Springfield, Illinois, 62702, United States
Southern Ohio Medical Center

Portsmouth, Ohio, 45662, United States
Spector, David MD (UIA Investigator)

Moline, Illinois, 61265, United States
Springfield Clinic

Springfield, Illinois, 62702, United States
Springfield Memorial Hospital

Springfield, Illinois, 62781, United States
Springfield Regional Medical Center

Springfield, Ohio, 45504, United States
Stony Brook University Medical Center

Stony Brook, New York, 11794, United States
Strecker Cancer Center-Belpre

Belpre, Ohio, 45714, United States
Summa Health System - Akron Campus

Akron, Ohio, 44304, United States
Swedish American Hospital

Rockford, Illinois, 61104, United States
Swedish Medical Center

Englewood, Colorado, 80113, United States
The Carle Foundation Hospital

Urbana, Illinois, 61801, United States
The Mark H Zangmeister Center

Columbus, Ohio, 43219, United States
The Medical Center of Aurora

Aurora, Colorado, 80012, United States
TidalHealth Nanticoke / Allen Cancer Center

Seaford, Delaware, 19973, United States
Toledo Clinic Cancer Centers-Bowling Green

Bowling Green, Ohio, 43402, United States
Toledo Clinic Cancer Centers-Maumee

Maumee, Ohio, 43537, United States
Toledo Clinic Cancer Centers-Monroe

Monroe, Michigan, 48162, United States
Toledo Clinic Cancer Centers-Oregon

Oregon, Ohio, 43616, United States
Toledo Clinic Cancer Centers-Toledo

Toledo, Ohio, 43623, United States
Toledo Community Hospital Oncology Program CCOP

Toledo, Ohio, 43617, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor

Ann Arbor, Michigan, 48106, United States
Trinity Health Saint Mary Mercy Livonia Hospital

Livonia, Michigan, 48154, United States
Trinity Medical Center

Moline, Illinois, 61265, United States
UI Health Care Mission Cancer and Blood - Des Moines Clinic

Des Moines, Iowa, 50309, United States
UI Health Care Mission Cancer and Blood - Laurel Clinic

Des Moines, Iowa, 50314, United States
UI Health Care Mission Cancer and Blood - West Des Moines Clinic

Clive, Iowa, 50325, United States
UW Health Carbone Cancer Center Rockford

Rockford, Illinois, 61114, United States
United Hospital

Saint Paul, Minnesota, 55102, United States
Unity Hospital

Fridley, Minnesota, 55432, United States
University of Alabama at Birmingham Cancer Center

Birmingham, Alabama, 35233, United States
University of Michigan Health - Sparrow Lansing

Lansing, Michigan, 48912, United States
University of Pittsburgh Cancer Institute (UPCI)

Pittsburgh, Pennsylvania, 15232, United States
University of Toledo

Toledo, Ohio, 43614, United States
University of Wisconsin Carbone Cancer Center - Johnson Creek

Johnson Creek, Wisconsin, 53038, United States
University of Wisconsin Carbone Cancer Center - University Hospital

Madison, Wisconsin, 53792, United States
Valley Radiation Oncology

Peru, Illinois, 61354, United States
Veterans Adminstration New Jersey Health Care System

East Orange, New Jersey, 07018-1095, United States
Vince Lombardi Cancer Clinic - Oshkosh

Oshkosh, Wisconsin, 54904, United States
Vince Lombardi Cancer Clinic-Sheboygan

Sheboygan, Wisconsin, 53081, United States
Vince Lombardi Cancer Clinic-Two Rivers

Two Rivers, Wisconsin, 54241, United States
West Virginia University Charleston Division

Charleston, West Virginia, 25304, United States
Western Illinois Cancer Treatment Center

Galesburg, Illinois, 61401, United States
Western States Cancer Research NCORP

Denver, Colorado, 80222, United States
Wichita NCI Community Oncology Research Program

Wichita, Kansas, 67214, United States
Woodland Cancer Care Center

Michigan City, Indiana, 46360, United States

Conditions

Explore the condition pages connected to this study.

RECURRENT MELANOMA STAGE IIIA CUTANEOUS MELANOMA AJCC V7 STAGE IIIB CUTANEOUS MELANOMA AJCC V7 STAGE IIIC CUTANEOUS MELANOMA AJCC V7 STAGE IV CUTANEOUS MELANOMA AJCC V6 AND V7