Less surgery may be just as good for advanced melanoma after immunotherapy
NCT ID NCT07049276
First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times
Summary
This study tests whether removing only the largest affected lymph node (instead of all nearby lymph nodes) after 6 weeks of standard immunotherapy works just as well for stage III melanoma. About 1500 adults with stage IIIB-D melanoma will be randomly assigned to one of the two surgeries. The goal is to see if the less extensive surgery can prevent cancer from coming back while causing fewer side effects like swelling and wound problems.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Calvary Mater Newcastle
RECRUITINGNewcastle, New South Wales, 2298, Australia
Contact Phone: •••-•••-••••
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Cedars-Sinai Medical Centre
NOT_YET_RECRUITINGLos Angeles, California, 90025, United States
Contact
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Fiona Stanley Hospital
RECRUITINGMurdoch, Western Australia, 6150, Australia
Contact Phone: •••-•••-••••
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Melanoma Institute Australia
RECRUITINGWollstonecraft, New South Wales, 2065, Australia
Contact
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San Maria della Misericordia Hospital
NOT_YET_RECRUITINGPerugia, Italy
Contact
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Sheba Medical centre
RECRUITINGRamat Gan, Tel Aviv, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sunnybrook Health Sciences Centre
NOT_YET_RECRUITINGToronto, Ontario, Canada
Contact
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The Royal Marsden
NOT_YET_RECRUITINGLondon, United Kingdom
Contact