Could a Two-Drug punch shrink melanoma before surgery?
NCT ID NCT04139902
First seen Nov 01, 2025 · Last updated Jun 09, 2026 · Updated 21 times
Summary
This study tests whether giving a combination of two immunotherapy drugs (dostarlimab and cobolimab) before surgery works better than one drug alone for people with stage III or IV melanoma that can be removed. The goal is to see if the combo can shrink or kill more of the tumor before surgery. About 48 adults with operable melanoma will take part.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Georgetown University Medical Center
Washington D.C., District of Columbia, 20007, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania, 15232, United States
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UPMC Hillman Cancer Center Washington
Washington, Pennsylvania, 15301, United States
Conditions
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