Drug duo vs. solo: the fight to stop deadly skin Cancer's return

NCT ID NCT05002569

Terminated Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

Summary

This study tested whether a two-drug immunotherapy combination works better than a single drug to prevent melanoma from returning after it has been surgically removed. It involved over 1,000 patients whose stage III or IV melanoma was completely cut out. The goal was to see which treatment keeps patients cancer-free for longer after surgery.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Dana-Farber Cancer Institute-Melanoma

Boston, Massachusetts, 02215, United States
Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States
Helsinki University Hospital Adult ICU PPDS

Helsinki, 00290, Finland
Icahn School Of Medicine At Mount Sinai

New York, New York, 10029, United States
Local Institution

Grand Rapids, Michigan, 49503, United States
Local Institution - 0001

CABA, Distrito Federal, C1430, Argentina
Local Institution - 0002

Ciudad de Buenos Aires, Distrito Federal, C1121ABE, Argentina
Local Institution - 0003

Ciudad Autónoma de Buenos Aires, Buenos Aires, C1426ABP, Argentina
Local Institution - 0004

Córdoba, X5002HWE, Argentina
Local Institution - 0005

Buenos Aires, Distrito Federal, 1426, Argentina
Local Institution - 0006

Santiago, Santiago Metropolitan, 8420383, Chile
Local Institution - 0009

Lørenskog, Akershus, 1478, Norway
Local Institution - 0010

Gothenburg, 41345, Sweden
Local Institution - 0011

Lund, 221 85, Sweden
Local Institution - 0012

Solna, 171 64, Sweden
Local Institution - 0013

Santiago, Santiago Metropolitan, 7510032, Chile
Local Institution - 0014

Santiago, Santiago Metropolitan, Chile
Local Institution - 0015

Turku, 20521, Finland
Local Institution - 0016

Aarhus, Central Jutland, 8200, Denmark
Local Institution - 0017

Oslo, 0310, Norway
Local Institution - 0018

Copenhagen, 2730, Denmark
Local Institution - 0019

Tampere, 33520, Finland
Local Institution - 0020

Odense, 5000, Denmark
Local Institution - 0021

Zapopan, Jalisco, 45070, Mexico
Local Institution - 0022

Aalborg, 9100, Denmark
Local Institution - 0023

Stavanger, Rogaland, 4011, Norway
Local Institution - 0026

Ostrava, 708 52, Czechia
Local Institution - 0027

Southport, Queensland, 4215, Australia
Local Institution - 0028

Brisbane, Queensland, 4102, Australia
Local Institution - 0029

Perth, Western Australia, 6009, Australia
Local Institution - 0030

Waratah, New South Wales, 2298, Australia
Local Institution - 0031

Melbourne, Victoria, 3000, Australia
Local Institution - 0032

Wollstonecraft, New South Wales, 2065, Australia
Local Institution - 0035

Ballarat, Victoria, 3350, Australia
Local Institution - 0039

Nantes, 44093, France
Local Institution - 0040

Villejuif, Val-de-Marne, 94800, France
Local Institution - 0041

Pierre-Bénite, 69310, France
Local Institution - 0042

Paris, 75010, France
Local Institution - 0043

Dijon, 21000, France
Local Institution - 0044

Marseille, 13385, France
Local Institution - 0046

Toulouse, 31100, France
Local Institution - 0047

Belo Horizonte, Minas Gerais, 30130-090, Brazil
Local Institution - 0048

Santa Cruz do Sul, Rio Grande do Sul, 96830-180, Brazil
Local Institution - 0049

Porto Alegre, Rio Grande do Sul, 91350-200, Brazil
Local Institution - 0056

Ijuí, Rio Grande do Sul, 98700-000, Brazil
Local Institution - 0058

Rio de Janeiro, 20220-410, Brazil
Local Institution - 0062

Prague, 12808, Czechia
Local Institution - 0064

Floresti/ Cluj, 407280, Romania
Local Institution - 0065

Cluj-Napoca, 400015, Romania
Local Institution - 0066

Craiova, 200542, Romania
Local Institution - 0068

Vitória, Espírito Santo, 29055450, Brazil
Local Institution - 0070

Barretos, São Paulo, 14784400, Brazil
Local Institution - 0071

Salvador, Estado de Bahia, 40170-070, Brazil
Local Institution - 0072

Fortaleza, Ceará, 60135237, Brazil
Local Institution - 0073

Buxtehude, 21614, Germany
Local Institution - 0074

Erlangen, 91054, Germany
Local Institution - 0075

Heidelberg, D-69120, Germany
Local Institution - 0076

Munich, 80337, Germany
Local Institution - 0077

Dresden, 01307, Germany
Local Institution - 0078

Lübeck, 23538, Germany
Local Institution - 0079

Hanover, Lower Saxony, 30625, Germany
Local Institution - 0080

Würzburg, 97080, Germany
Local Institution - 0081

Gera, 07548, Germany
Local Institution - 0082

Graz, Styria, 8036, Austria
Local Institution - 0083

Minden, 32429, Germany
Local Institution - 0084

Vienna, 1090, Austria
Local Institution - 0085

Basel, 4031, Switzerland
Local Institution - 0086

Salzburg, 5020, Austria
Local Institution - 0087

Chur, 7000, Switzerland
Local Institution - 0090

Zurich, 8091, Switzerland
Local Institution - 0091

Hradec Králové, 50005, Czechia
Local Institution - 0092

Tübingen, Baden-Wurttemberg, 72076, Germany
Local Institution - 0093

México, Nuevo León, 64320, Mexico
Local Institution - 0098

Oaxaca City, 68020, Mexico
Local Institution - 0100

Benito Juárez, Mexico City, 03240, Mexico
Local Institution - 0101

Nottingham, Nottinghamshire, NG5 1PB, United Kingdom
Local Institution - 0102

Bristol, BS2 8ED, United Kingdom
Local Institution - 0105

Brussels, 1200, Belgium
Local Institution - 0106

Wilrijk, 2610, Belgium
Local Institution - 0109

Liège, 4000, Belgium
Local Institution - 0110

Brussels, 1090, Belgium
Local Institution - 0112

Thessaloniki, 540 07, Greece
Local Institution - 0113

Neo Faliro, 185 47, Greece
Local Institution - 0114

Athens, 11527, Greece
Local Institution - 0115

Milan, 20133, Italy
Local Institution - 0116

Afula, 1834111, Israel
Local Institution - 0117

Ramat Gan, 5262100, Israel
Local Institution - 0118

Jerusalem, Jerusalem, 9112001, Israel
Local Institution - 0119

Naples, 80131, Italy
Local Institution - 0120

Padua, 35128, Italy
Local Institution - 0121

Siena, 53100, Italy
Local Institution - 0122

Perugia, 06132, Italy
Local Institution - 0123

Milan, 20141, Italy
Local Institution - 0125

Pittsburgh, Pennsylvania, 15232, United States
Local Institution - 0127

Southampton, SO16 0YD, United Kingdom
Local Institution - 0130

Charlotte, North Carolina, 28204, United States
Local Institution - 0131

Essen, 45147, Germany
Local Institution - 0133

Minneapolis, Minnesota, 55407, United States
Local Institution - 0137

Fairfax, Virginia, 22031, United States
Local Institution - 0138

Aurora, Colorado, 80045, United States
Local Institution - 0139

Hackensack, New Jersey, 07601, United States
Local Institution - 0140

New York, New York, 10016, United States
Local Institution - 0141

Cleveland, Ohio, 44195, United States
Local Institution - 0145

Durham, North Carolina, 27710, United States
Local Institution - 0146

Austin, Texas, 78731, United States
Local Institution - 0147

Germantown, Tennessee, 38138, United States
Local Institution - 0148

Atlanta, Georgia, 30342, United States
Local Institution - 0150

Madrid, 28009, Spain
Local Institution - 0151

Donostia / San Sebastian, 20014, Spain
Local Institution - 0152

Valencia, 46026, Spain
Local Institution - 0153

Granada, 18012, Spain
Local Institution - 0154

Newcastle upon Tyne, NE7 7DN, United Kingdom
Local Institution - 0155

Edmonton, Alberta, T6X 1E8, Canada
Local Institution - 0156

Brno, 65653, Czechia
Local Institution - 0158

Montreal, Quebec, H3T 1E2, Canada
Local Institution - 0159

Montreal, Quebec, H2X 1P1, Canada
Local Institution - 0160

Québec, Quebec, G1J 1Z4, Canada
Local Institution - 0162

San Francisco, California, 94115, United States
Local Institution - 0163

Dallas, Texas, 75246, United States
Local Institution - 0164

Springdale, Arkansas, 72762, United States
Local Institution - 0166

Washington D.C., District of Columbia, 20007, United States
Local Institution - 0170

Brasov, 500283, Romania
Local Institution - 0171

Charleston, South Carolina, 29425, United States
Local Institution - 0172

Houston, Texas, 77030, United States
Local Institution - 0175

Vancouver, British Columbia, V5Z 4E6, Canada
Local Institution - 0176

Birmingham, Alabama, 35249, United States
Local Institution - 0177

Peoria, Illinois, 61615, United States
Local Institution - 0178

Westwood, Kansas, 66205, United States
Local Institution - 0179

Pensacola, Florida, 32504, United States
Local Institution - 0183

Nashville, Tennessee, 37232, United States
Local Institution - 0185

Palo Alto, California, 94304, United States
Local Institution - 0187

Glasgow, G12 0YN, United Kingdom
Local Institution - 0188

Badajoz, 06071, Spain
Local Institution - 0191

Atlanta, Georgia, 30322, United States
Local Institution - 0197

Halifax, Nova Scotia, B3H 2Y9, Canada
Local Institution - 0198

Sherbrooke, Quebec, J1H 5N4, Canada
Local Institution - 0199

Petah Tikva, Central District, 4941492, Israel
Local Institution - 0200

Los Angeles, California, 90025, United States
Local Institution - 0201

Barcelona, 08035, Spain
Local Institution - 0202

Chicago, Illinois, 60611, United States
Local Institution - 0206

Morristown, New Jersey, 07960, United States
Local Institution - 0210

New York, New York, 10065, United States
Local Institution - 0214

Beijing, Beijing Municipality, 100142, China
Local Institution - 0215

Nanjing, Jiangsu, 210000, China
Local Institution - 0216

Hangzhou, Zhejiang, 310022, China
Local Institution - 0217

Guangzhou, Guangdong, 510060, China
Local Institution - 0219

Changchun, Jilin, 130021, China
Local Institution - 0220

Hangzhou, Zhejiang, 310016, China
Local Institution - 0221

Hefei, Anhui, 230022, China
Local Institution - 0222

Kunming, Yunnan, 650106, China
Local Institution - 0223

Fort Wayne, Indiana, 46804, United States
Local Institution - 0224

Nanchang, Jiangxi, 330006, China
Local Institution - 0225

Nanjing, Jiangsu, 210029, China
Local Institution - 0226

Zhengzhou, Henan, 450001, China
Local Institution - 0228

Ürümqi, Xinjiang, 830000, China
Local Institution - 0230

Chengdu, Sichuan, 610041, China
Local Institution - 0232

Oxford, OX3 7LE, United Kingdom
Local Institution - 0234

Changsha Shi, Hunan, 410013, China
Local Institution - 0237

Wuhan, Hubei, 430022, China
Local Institution - 0239

Wuhan, Hubei, 430030, China
Local Institution - 0241

Chongqing, Chongqing Municipality, 400030, China
Local Institution - 0242

Shenyang, Liaoning, 110001, China
Local Institution - 0243

Miami, Florida, 33136, United States
Local Institution - 0244

Taiyuan, 030032, China
Local Institution - 0245

Fuzhou, Fujian, 350014, China
Local Institution - 0249

Coimbra, 3000-075, Portugal
Local Institution - 0250

Woodville, South Australia, 5011, Australia
Local Institution - 0251

Murdoch, Western Australia, 6150, Australia
Local Institution - 0252

Westmead, New South Wales, 2145, Australia
Local Institution - 0253

Heidelberg, Victoria, 3084, Australia
Local Institution - 0254

Tiwi, Northern Territory, 0810, Australia
Local Institution - 0257

Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
Local Institution - 0258

Ann Arbor, Michigan, 48109, United States
Local Institution - 0259

Beijing, Beijing Municipality, 100034, China
Local Institution - 0261

Beijing, Beijing Municipality, 100035, China
Local Institution - 0263

Tianjin, Tianjin Municipality, 300060, China
Local Institution - 0267

Allentown, Pennsylvania, 18103, United States
Local Institution - 0268

Milan, 20133, Italy
MetroHealth Medical Center

Cleveland, Ohio, 44109, United States
Moffitt Cancer Center, Richard M. Shulze Family Foundation Outpatient Center

Tampa, Florida, 33612, United States
Saint John's Cancer Institute

Santa Monica, California, 90404, United States
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C

Columbus, Ohio, 43210, United States
University of Iowa-Holden Comprehensive Cancer Center

Iowa City, Iowa, 52242, United States
Washington University School Of Medicine

Miami, Florida, 33136, United States

Conditions

Explore the condition pages connected to this study.

MELANOMA