New drug combo aims to control advanced skin cancer

NCT ID NCT03149029

Summary

This study is testing whether a short course of two targeted cancer drugs (trametinib and dabrafenib), given alongside an immunotherapy drug (pembrolizumab), works better than expected for people with advanced melanoma that cannot be removed by surgery. The goal is to see if this combination helps control the cancer for a longer period. All 16 participants have advanced melanoma with a specific genetic change (BRAF mutation).

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02115, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Massachusetts general Hospital

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.