New hope for kids with tough brain tumors: pill shows promise

NCT ID NCT02285439

Summary

This study tested an oral drug called MEK162 in children whose low-grade brain tumors had come back or grown after standard treatment. The main goals were to find a safe dose for kids and to see if the drug could shrink these tumors. About 105 children took the pill twice a day for up to two years while doctors monitored their response.

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Contacts and locations

Locations

  • Children's Healthcare of Atlanta

    Atlanta, Georgia, 30322, United States

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital of Alabama

    Birmingham, Alabama, 35233, United States

  • Children's Hospital of Colorado

    Aurora, Colorado, 80045, United States

  • Children's Hospitals and Clinics of Minnesota-Minneapolis

    Minneapolis, Minnesota, 55404, United States

  • Children's National Heath Systems

    Washington D.C., District of Columbia, 20010, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

  • New York University

    New York, New York, 10016, United States

  • Nicklaus Children's Hospital

    Miami, Florida, 33155, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Seattle Children's Hospital

    Seattle, Washington, 98145, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • University of Texas Southwestern Medical

    Dallas, Texas, 75390, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.