New combo therapy tested for hard-to-treat colorectal cancer

NCT ID NCT02613650

First seen May 14, 2026 · Last updated Jun 11, 2026 · Updated 5 times

Summary

This early-phase trial tested a combination of two drugs (MEK162 and mFOLFIRI) in 25 adults with advanced RAS-positive colorectal cancer that had stopped responding to standard treatment. The main goal was to find the safest dose and check for side effects. Researchers also looked at whether tumors shrank or stayed stable.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADVANCED KRAS POSITIVE METASTATIC COLORECTAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Huntsman Cancer Institute

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.