New combo therapy shows promise for tough leukemia cases

NCT ID NCT03118466

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 42 times

Summary

This study tested whether adding the drug lenalidomide to a standard chemotherapy regimen (MEC) could help adults with acute myeloid leukemia (AML) that had come back or not responded to prior treatment. 41 patients took part. The main goal was to see how many achieved complete remission (no signs of leukemia) or complete remission without full platelet recovery. The study is complete, and results help guide future treatment options for this difficult-to-treat cancer.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02062, United States

  • Massachusetts general Hospital

    Boston, Massachusetts, 02215, United States

Conditions

Explore the condition pages connected to this study.