New antibody trial aims to block severe COVID-19

NCT ID NCT07445971

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study is testing an experimental antibody called MDX2301 to see if it can help prevent severe COVID-19 in healthy adults and those at higher risk. About 80 participants will receive either the antibody or a placebo, given as an injection or infusion. The main goal is to check safety and how the body processes the drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MDX2301 (an experimental antibody)

What this could lead to

If successful, this could lead to a new antibody-based prevention for severe COVID-19, especially for people at higher risk.

What could go wrong

This is a very early Phase 1 study with only 80 participants, so safety and effectiveness are not yet proven. The results may not lead to a widely available treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

COVID-19 prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • TrialMed Clinical Research Unit

    RECRUITING

    Las Vegas, Nevada, 89113, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • TrialMed Clinical Research Unit

    RECRUITING

    Austin, Texas, 78744, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••