New Two-Drug attack on rare blood cancer shows promise

NCT ID NCT06577441

Recruiting now Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study is testing if adding a new drug, enasidenib, to a standard treatment works better for controlling a high-risk type of myelodysplastic syndrome (MDS), a bone marrow disorder. It will involve about 54 adults with a specific genetic change (IDH2 mutation) who have not had certain prior treatments. The main goal is to see which approach leads to more patients achieving a complete remission, meaning no detectable signs of the disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Alta Bates Summit Medical Center-Herrick Campus
RECRUITING

Berkeley, California, 94704, United States

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BJC Outpatient Center at Sunset Hills
RECRUITING

Sunset Hills, Missouri, 63127, United States

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Contact Phone: •••-•••-••••
Benefis Sletten Cancer Institute
RECRUITING

Great Falls, Montana, 59405, United States

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Billings Clinic Cancer Center
RECRUITING

Billings, Montana, 59101, United States

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Bozeman Health Deaconess Hospital
RECRUITING

Bozeman, Montana, 59715, United States

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Cancer Care Center of O'Fallon
RECRUITING

O'Fallon, Illinois, 62269, United States

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Cancer Care Specialists of Illinois - Decatur
RECRUITING

Decatur, Illinois, 62526, United States

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Cancer Hematology Centers - Flint
RECRUITING

Flint, Michigan, 48503, United States

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Carle Cancer Center
RECRUITING

Urbana, Illinois, 61801, United States

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Carle Physician Group-Mattoon/Charleston
RECRUITING

Mattoon, Illinois, 61938, United States

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Carle at The Riverfront
RECRUITING

Danville, Illinois, 61832, United States

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Centro Comprensivo de Cancer de UPR
RECRUITING

San Juan, 00927, Puerto Rico

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Community Hospital of Anaconda
RECRUITING

Anaconda, Montana, 59711, United States

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Community Medical Center
RECRUITING

Missoula, Montana, 59804, United States

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Community Medical Center
RECRUITING

Toms River, New Jersey, 08755, United States

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Crossroads Cancer Center
RECRUITING

Effingham, Illinois, 62401, United States

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Decatur Memorial Hospital
RECRUITING

Decatur, Illinois, 62526, United States

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Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States

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Duluth Clinic Ashland
RECRUITING

Ashland, Wisconsin, 54806, United States

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East Carolina University
RECRUITING

Greenville, North Carolina, 27834, United States

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Essentia Health - Deer River Clinic
RECRUITING

Deer River, Minnesota, 56636, United States

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Essentia Health Cancer Center
RECRUITING

Duluth, Minnesota, 55805, United States

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Essentia Health Cancer Center-South University Clinic
RECRUITING

Fargo, North Dakota, 58103, United States

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Essentia Health Hibbing Clinic
RECRUITING

Hibbing, Minnesota, 55746, United States

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Essentia Health Saint Joseph's Medical Center
RECRUITING

Brainerd, Minnesota, 56401, United States

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Essentia Health Sandstone
RECRUITING

Sandstone, Minnesota, 55072, United States

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Essentia Health Virginia Clinic
RECRUITING

Virginia, Minnesota, 55792, United States

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Geisinger Medical Center
RECRUITING

Danville, Pennsylvania, 17822, United States

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Geisinger Wyoming Valley/Henry Cancer Center
RECRUITING

Wilkes-Barre, Pennsylvania, 18711, United States

Contact

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Genesee Hematology Oncology PC
SUSPENDED

Flint, Michigan, 48503, United States
Genesys Hurley Cancer Institute
RECRUITING

Flint, Michigan, 48503, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Gundersen Lutheran Medical Center
RECRUITING

La Crosse, Wisconsin, 54601, United States

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HSHS Saint Elizabeth's Hospital
RECRUITING

O'Fallon, Illinois, 62269, United States

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Hennepin County Medical Center
RECRUITING

Minneapolis, Minnesota, 55415, United States

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Huntsman Cancer Institute/University of Utah
RECRUITING

Salt Lake City, Utah, 84112, United States

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Illinois CancerCare - Washington
RECRUITING

Washington, Illinois, 61571, United States

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Illinois CancerCare-Bloomington
RECRUITING

Bloomington, Illinois, 61704, United States

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Illinois CancerCare-Canton
RECRUITING

Canton, Illinois, 61520, United States

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Illinois CancerCare-Carthage
RECRUITING

Carthage, Illinois, 62321, United States

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Illinois CancerCare-Dixon
RECRUITING

Dixon, Illinois, 61021, United States

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Illinois CancerCare-Eureka
RECRUITING

Eureka, Illinois, 61530, United States

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Illinois CancerCare-Galesburg
RECRUITING

Galesburg, Illinois, 61401, United States

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Illinois CancerCare-Kewanee Clinic
RECRUITING

Kewanee, Illinois, 61443, United States

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Illinois CancerCare-Macomb
RECRUITING

Macomb, Illinois, 61455, United States

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Illinois CancerCare-Ottawa Clinic
RECRUITING

Ottawa, Illinois, 61350, United States

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Illinois CancerCare-Pekin
RECRUITING

Pekin, Illinois, 61554, United States

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Illinois CancerCare-Peoria
RECRUITING

Peoria, Illinois, 61615, United States

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Illinois CancerCare-Peru
RECRUITING

Peru, Illinois, 61354, United States

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Illinois CancerCare-Princeton
RECRUITING

Princeton, Illinois, 61356, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
Iowa Methodist Medical Center
RECRUITING

Des Moines, Iowa, 50309, United States

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Contact Phone: •••-•••-••••
Kootenai Clinic Cancer Services - Post Falls
RECRUITING

Post Falls, Idaho, 83854, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Kootenai Clinic Cancer Services - Sandpoint
RECRUITING

Sandpoint, Idaho, 83864, United States

Contact

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Kootenai Health - Coeur d'Alene
RECRUITING

Coeur d'Alene, Idaho, 83814, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
LSU Health Baton Rouge-North Clinic
SUSPENDED

Baton Rouge, Louisiana, 70805, United States
Logan Health Medical Center
RECRUITING

Kalispell, Montana, 59901, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Loyola University Medical Center
RECRUITING

Maywood, Illinois, 60153, United States

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Marshfield Medical Center - Weston
RECRUITING

Weston, Wisconsin, 54476, United States

Contact

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Marshfield Medical Center-River Region at Stevens Point
RECRUITING

Stevens Point, Wisconsin, 54482, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Medical College of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States

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Contact Phone: •••-•••-••••
Memorial Hospital West
RECRUITING

Pembroke Pines, Florida, 33028, United States

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Contact Phone: •••-•••-••••
Mercy Medical Center - Des Moines
RECRUITING

Des Moines, Iowa, 50314, United States

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Contact Phone: •••-•••-••••
Miami Cancer Institute
RECRUITING

Miami, Florida, 33176, United States

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Contact Phone: •••-•••-••••
Mills Health Center
RECRUITING

San Mateo, California, 94401, United States

Contact

Contact Email: •••••@•••••
Missouri Baptist Medical Center
RECRUITING

St Louis, Missouri, 63131, United States

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Contact Phone: •••-•••-••••
Missouri Baptist Sullivan Hospital
RECRUITING

Sullivan, Missouri, 63080, United States

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Contact Phone: •••-•••-••••
Monmouth Medical Center
RECRUITING

Long Branch, New Jersey, 07740, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
NorthShore University HealthSystem-Evanston Hospital
RECRUITING

Evanston, Illinois, 60201, United States

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Contact Phone: •••-•••-••••
NorthShore University HealthSystem-Glenbrook Hospital
RECRUITING

Glenview, Illinois, 60026, United States

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Contact Phone: •••-•••-••••
NorthShore University HealthSystem-Highland Park Hospital
RECRUITING

Highland Park, Illinois, 60035, United States

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Contact Phone: •••-•••-••••
Northwestern Medicine Cancer Center Delnor
RECRUITING

Geneva, Illinois, 60134, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Northwestern Medicine Cancer Center Kishwaukee
RECRUITING

DeKalb, Illinois, 60115, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Northwestern Medicine Cancer Center Warrenville
RECRUITING

Warrenville, Illinois, 60555, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Northwestern Medicine Glenview Outpatient Center
RECRUITING

Glenview, Illinois, 60026, United States

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Northwestern Medicine Grayslake Outpatient Center
RECRUITING

Grayslake, Illinois, 60030, United States

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Northwestern Medicine Lake Forest Hospital
RECRUITING

Lake Forest, Illinois, 60045, United States

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Northwestern Medicine Orland Park
RECRUITING

Orland Park, Illinois, 60462, United States

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Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Ohio State University Comprehensive Cancer Center
RECRUITING

Columbus, Ohio, 43210, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
Our Lady of The Lake
RECRUITING

Baton Rouge, Louisiana, 70808, United States

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Our Lady of the Lake Physician Group
RECRUITING

Baton Rouge, Louisiana, 70808, United States

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Parkland Health Center - Farmington
RECRUITING

Farmington, Missouri, 63640, United States

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Phoebe Putney Memorial Hospital
RECRUITING

Albany, Georgia, 31701, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Prisma Health Cancer Institute - Butternut
RECRUITING

Greenville, South Carolina, 29605, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Prisma Health Cancer Institute - Easley
RECRUITING

Easley, South Carolina, 29640, United States

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Prisma Health Cancer Institute - Eastside
RECRUITING

Greenville, South Carolina, 29615, United States

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Prisma Health Cancer Institute - Faris
RECRUITING

Greenville, South Carolina, 29605, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Prisma Health Cancer Institute - Greer
RECRUITING

Greer, South Carolina, 29650, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Prisma Health Cancer Institute - Seneca
RECRUITING

Seneca, South Carolina, 29672, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Prisma Health Cancer Institute - Spartanburg
RECRUITING

Boiling Springs, South Carolina, 29316, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Roswell Park Cancer Institute
RECRUITING

Buffalo, New York, 14263, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08903, United States

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Contact Phone: •••-•••-••••
Saint Alphonsus Cancer Care Center-Nampa
RECRUITING

Nampa, Idaho, 83687, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Saint Barnabas Medical Center
RECRUITING

Livingston, New Jersey, 07039, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Saint Luke's Cancer Institute - Boise
RECRUITING

Boise, Idaho, 83712, United States

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Saint Luke's Cancer Institute - Fruitland
RECRUITING

Fruitland, Idaho, 83619, United States

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Saint Luke's Cancer Institute - Meridian
RECRUITING

Meridian, Idaho, 83642, United States

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Saint Luke's Cancer Institute - Nampa
RECRUITING

Nampa, Idaho, 83687, United States

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Saint Vincent Hospital Cancer Center Green Bay
RECRUITING

Green Bay, Wisconsin, 54301, United States

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Saint Vincent Hospital Cancer Center at Saint Mary's
RECRUITING

Green Bay, Wisconsin, 54303, United States

Contact

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Sainte Genevieve County Memorial Hospital
RECRUITING

Sainte Genevieve, Missouri, 63670, United States

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Contact Phone: •••-•••-••••
San Juan City Hospital
RECRUITING

San Juan, 00936, Puerto Rico

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Contact Phone: •••-•••-••••
Southern Illinois University School of Medicine
RECRUITING

Springfield, Illinois, 62702, United States

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Contact Phone: •••-•••-••••
Springfield Clinic
RECRUITING

Springfield, Illinois, 62702, United States

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Contact Phone: •••-•••-••••
Springfield Memorial Hospital
RECRUITING

Springfield, Illinois, 62781, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Swedish Cancer Institute-Edmonds
RECRUITING

Edmonds, Washington, 98026, United States

Contact

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Swedish Cancer Institute-Issaquah
RECRUITING

Issaquah, Washington, 98029, United States

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Swedish Covenant Hospital
RECRUITING

Chicago, Illinois, 60625, United States

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Swedish Medical Center-First Hill
RECRUITING

Seattle, Washington, 98122, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
The James Graham Brown Cancer Center at University of Louisville
SUSPENDED

Louisville, Kentucky, 40202, United States
Trinity Health IHA Medical Group Hematology Oncology - Brighton
RECRUITING

Brighton, Michigan, 48114, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Trinity Health IHA Medical Group Hematology Oncology - Canton
RECRUITING

Canton, Michigan, 48188, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
RECRUITING

Chelsea, Michigan, 48118, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
RECRUITING

Ypsilanti, Michigan, 48197, United States

Contact

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Trinity Health Saint Joseph Mercy Oakland Hospital
RECRUITING

Pontiac, Michigan, 48341, United States

Contact

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Trinity Health Saint Mary Mercy Livonia Hospital
RECRUITING

Livonia, Michigan, 48154, United States

Contact

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Tufts Medical Center
RECRUITING

Boston, Massachusetts, 02111, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
UC Comprehensive Cancer Center at Silver Cross
RECRUITING

New Lenox, Illinois, 60451, United States

Contact

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UC Irvine Health/Chao Family Comprehensive Cancer Center
RECRUITING

Orange, California, 92868, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
RECRUITING

Irvine, California, 92612, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
UChicago Medicine Northwest Indiana
RECRUITING

Crown Point, Indiana, 46307, United States

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UF Health Cancer Institute - Gainesville
RECRUITING

Gainesville, Florida, 32610, United States

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UI Health Care Mission Cancer and Blood - Ankeny Clinic
RECRUITING

Ankeny, Iowa, 50023, United States

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UI Health Care Mission Cancer and Blood - Des Moines Clinic
RECRUITING

Des Moines, Iowa, 50309, United States

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UI Health Care Mission Cancer and Blood - Laurel Clinic
RECRUITING

Des Moines, Iowa, 50314, United States

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UI Health Care Mission Cancer and Blood - Waukee Clinic
RECRUITING

Waukee, Iowa, 50263, United States

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UI Health Care Mission Cancer and Blood - West Des Moines Clinic
RECRUITING

Clive, Iowa, 50325, United States

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Contact Phone: •••-•••-••••
University of Chicago Comprehensive Cancer Center
RECRUITING

Chicago, Illinois, 60637, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Chicago Medicine-Orland Park
RECRUITING

Orland Park, Illinois, 60462, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Iowa/Holden Comprehensive Cancer Center
RECRUITING

Iowa City, Iowa, 52242, United States

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Contact Phone: •••-•••-••••
University of New Mexico Cancer Center
RECRUITING

Albuquerque, New Mexico, 87106, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Oklahoma Health Sciences Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States

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Contact
University of Pittsburgh Cancer Institute (UPCI)
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States

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Contact Phone: •••-•••-••••
University of Tennessee - Knoxville
RECRUITING

Knoxville, Tennessee, 37920, United States

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UofL Health Medical Center Northeast
SUSPENDED

Louisville, Kentucky, 40245, United States
VCU Massey Comprehensive Cancer Center
RECRUITING

Richmond, Virginia, 23298, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Walter Reed National Military Medical Center
RECRUITING

Bethesda, Maryland, 20889-5600, United States

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Contact Phone: •••-•••-••••
William S Middleton VA Medical Center
RECRUITING

Madison, Wisconsin, 53705, United States

Contact

Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

MYELODYSPLASTIC SYNDROME