Can a simple blood test predict cancer risk from radiation therapy?

NCT ID NCT06510868

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is for people with neuroendocrine tumors who are about to receive or have already received peptide receptor radionuclide therapy (PRRT). Researchers want to find out if certain genetic changes in the blood can predict who might later develop myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML), two types of blood cancer. About 45 participants will give blood samples over several years to look for these genetic markers. The goal is not to treat the blood cancers, but to better understand the risks and improve patient care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify which patients are at higher risk of developing blood cancers after PRRT, allowing safer treatment choices.
What could go wrong
This is a small observational study, not a treatment trial. It may not find clear genetic markers, and results may not apply to all patients or treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Princess Margaret Cancer Centre

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

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