New depression pill hopes to lift the fog when antidepressants fall short
NCT ID NCT06911112
First seen Jan 05, 2026 · Last updated May 15, 2026 · Updated 20 times
Summary
This study tests whether a new drug called NBI-1065845 can improve depression symptoms in adults who still feel depressed despite taking standard antidepressants. About 200 participants will receive either the study drug or a placebo pill alongside their usual medication for 8 weeks. The main goal is to see if the drug reduces depression scores more than placebo.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Neurocrine Clinical Site
RECRUITINGHuntsville, Alabama, 35801, United States
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Neurocrine Clinical Site
RECRUITINGGlendale, California, 91206, United States
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Neurocrine Clinical Site
RECRUITINGIrvine, California, 92614, United States
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Neurocrine Clinical Site
RECRUITINGMiami, Florida, 33174, United States
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Neurocrine Clinical Site
RECRUITINGTampa, Florida, 33607, United States
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Neurocrine Clinical Site
RECRUITINGAtlanta, Georgia, 30318, United States
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Neurocrine Clinical Site
RECRUITINGBoston, Massachusetts, 02131, United States
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Neurocrine Clinical Site
RECRUITINGSaint Charles, Missouri, 63304, United States
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Neurocrine Clinical Site
RECRUITINGThe Bronx, New York, 10461, United States
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Neurocrine Clinical Site
RECRUITINGMason, Ohio, 45040, United States
Conditions
Explore the condition pages connected to this study.