New drug trial targets liver scarring in MASH patients

NCT ID NCT06903065

Ongoing Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times

Summary

This early-stage study tests a new medicine called RO7790121 in 50 adults with advanced liver scarring from MASH (a type of fatty liver disease). The main goal is to see if the drug is safe and how the body processes it. Researchers will also check if it can reduce liver stiffness and improve markers of liver damage.

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Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatohepatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MASH

Contacts and locations

Locations

Adobe Clinical Research, LLC

Tucson, Arizona, 85712, United States
Bellaire Clinical Research, LLC

Bellaire, Texas, 77401, United States
Centro de Investigacion y Gastroenterologia

Mexico City, Mexico CITY (federal District), 06700, Mexico
DHR Health Institute for Research and Development

McAllen, Texas, 78504, United States
Delta Research Partners, LLC (Bastrop)

Bastrop, Louisiana, 71220, United States
FDI Clinicial Research - Mayaguez

Mayagez, 00680, Puerto Rico
Fundacion Santos Y De La Garza Evia IBP

San Pedro Garza García, Nuevo León, 66278, Mexico
Fundacion de Investigacion de Diego

San Juan, 00927, Puerto Rico
GI Alliance

Southlake, Texas, 76092, United States
Gastrointestinal Specialists of Georgia, PC

Marietta, Georgia, 30060, United States
Innovative Clinical Research

Clarksville, Tennessee, 37040, United States
Jubilee Clinical Research NV, LLC

Las Vegas, Nevada, 89106, United States
Pinnacle Clinical Research - Austin

Austin, Texas, 78757, United States
Pinnacle Clinical Research Georgetown

Georgetown, Texas, 78626, United States
Pinnacle Clinical Research, PLLC

San Antonio, Texas, 78229, United States

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