New MRI-Guided radiation aims to zap sarcomas with pinpoint accuracy

NCT ID NCT06436612

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This phase 2 trial tests a precise radiation technique called MRI-guided stereotactic body radiation therapy (SBRT) for people with sarcomas in the abdomen or pelvis. The radiation is given over 5 days, followed by surgery within 12 weeks. The goal is to safely deliver high-dose radiation to the tumor while sparing healthy organs. Researchers will track side effects and tumor control for up to 5 years.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
MRI-guided stereotactic body radiation therapy (SBRT)
What this could lead to
If successful, this approach could offer a more precise, safer way to treat sarcomas in the abdomen and pelvis, potentially reducing side effects and improving tumor control.
What could go wrong
This is a small, early-phase trial with only 20 participants, so results may not apply to everyone. The treatment still requires surgery afterward, and there is a risk of radiation-related side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UCLA / Jonsson Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90095, United States