Scientists investigate why rare lung disease develops in children

NCT ID NCT04811274

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 32 times

Summary

This study looked at 20 children with a rare lung condition called pulmonary alveolar proteinosis (PAP) caused by changes in the MARS gene. Researchers wanted to understand if the lung cleaning cells (macrophages) are not working properly. They grew these cells in a lab from blood samples and tested how well they cleaned up fatty material. This was a research-only study, not a treatment trial.

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Contacts and locations

Locations

  • Hôpital Necker-Enfants Malades

    Paris, 75015, France

Conditions

Explore the condition pages connected to this study.