Could an HIV drug protect new lungs after transplant?

NCT ID NCT06853223

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether Maraviroc, a drug already approved for HIV, can prevent a serious lung injury called primary graft dysfunction (PGD) after a lung transplant. PGD is a major cause of death in the first year after transplant, and there are no approved treatments for it. About 120 adults getting a double lung transplant will receive either Maraviroc or a placebo for 3 days after surgery. Researchers will compare how many develop severe PGD and how well they recover.

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Conditions

The condition(s) this trial relates to.

acute lung injury Primary Graft Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

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