New hope for Moms-to-Be with dangerous itching condition?

NCT ID NCT07389031

First seen Feb 05, 2026 · Last updated Apr 28, 2026 · Updated 13 times

Summary

This early-phase trial tests whether maralixibat is safe and can reduce severe itching in pregnant women with intrahepatic cholestasis of pregnancy (ICP), a liver condition that raises bile acids. About 28 women with a single pregnancy between 20 and 35 weeks will take the drug. The main goal is to check for side effects and see if itching improves.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Birmingham Womens and Childrens NHS Foundation Trust

    Birmingham, B15 2TG, United Kingdom

  • Guy's and St Thomas' NHS Foundation Trust

    London, SE 1 7EH, United Kingdom

Conditions

Explore the condition pages connected to this study.