New hope for depression when standard drugs fail

NCT ID NCT03870776

Summary

This study tested whether a daily oral medication called MAP4343 could help reduce symptoms in people with major depression who did not respond to at least two standard antidepressant treatments. For 6 weeks, 126 participants either received MAP4343 or a placebo pill, without knowing which one they were taking. Researchers measured changes in depression and anxiety scores, along with safety checks, to see if the new drug offered relief where other treatments had not.

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Contacts and locations

Locations

  • APHP Hôpital La Pitié Salpétrière - Prinicipal investigator center

    Paris, 75013, France

  • CHD Vendée

    La Roche-sur-Yon, 85000, France

  • CHRU Tours

    Tours, 37000, France

  • CHU Angers

    Angers, 49900, France

  • CHU Besançon

    Besançon, 25000, France

  • CHU Henri Laborit

    Poitiers, 86000, France

  • CHU Nantes

    Nantes, 44000, France

  • Cabinet Médical Ambroise Paré

    Élancourt, 78990, France

  • Hôpital Fontan 1

    Lille, 59000, France

  • Hôpital Ste Anne

    Paris, 75014, France

Conditions

Explore the condition pages connected to this study.