New study aims to tame skin rashes from lung cancer drugs

NCT ID NCT06120140

Recruiting now Symptom relief Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 28 times

Summary

This study tests whether special skin care can reduce rashes and other skin problems caused by a lung cancer drug combination (amivantamab + lazertinib). About 300 people with advanced EGFR-mutated non-small cell lung cancer will be randomly assigned to standard skin care or enhanced skin care. The goal is to see if the enhanced approach lowers the chance of moderate-to-severe skin side effects.

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Contacts and locations

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Study contacts

Contact

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Locations

Adana City Hospital
RECRUITING

Adana, 1060, Turkey (Türkiye)
Ankara Bilkent City Hospital
RECRUITING

Ankara, 6800, Turkey (Türkiye)
Associacao Feminina de Educacao e Combate ao Cancer Hospital Santa Rita de Cassia
RECRUITING

Vitória, 29043-260, Brazil
Bakirkoy Training and Research Hospital
RECRUITING

Istanbul, 34147, Turkey (Türkiye)
CTO Centro De Tratamento Oncologico LTDA
RECRUITING

Belém, 66.073-005, Brazil
Cancer and Blood Specialty Clinic
RECRUITING

Los Alamitos, California, 90720, United States
Centro Medico Austral
RECRUITING

Capital Federal, C1017, Argentina
Chang Gung Memorial Hospital
RECRUITING

Kaohsiung City, 833, Taiwan
Changzhou No 2 Peoples Hospital
RECRUITING

Changzhou, 213004, China
Chungbuk National University Hospital
RECRUITING

Cheongju-si, 28644, South Korea
City of Hope
RECRUITING

Duarte, California, 91010, United States
City of Hope Long Beach Elm
RECRUITING

Long Beach, California, 90813, United States
City of Hope Orange County Lennar Foundation Cancer Center
RECRUITING

Irvine, California, 92618, United States
City of Hope Seacliff
RECRUITING

Huntington Beach, California, 92648, United States
City of Hope South Pasadena
RECRUITING

South Pasadena, California, 91030, United States
Clinical Research Alliance Inc
COMPLETED

Westbury, New York, 11590, United States
Ege University Medical Faculty
RECRUITING

Izmir, 35100, Turkey (Türkiye)
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, 200032, China
Fundacao Antonio Prudente A C Camargo Cancer Center
RECRUITING

São Paulo, 01509 900, Brazil
Fundacao Doutor Amaral Carvalho
RECRUITING

Jaú, 17.210-080, Brazil
Fundacao Faculdade de Medicina - Instituto do Cancer do Estado de Sao Paulo
RECRUITING

São Paulo, 01246 000, Brazil
Gachon University Gil Medical Center
RECRUITING

Incheon, 21565, South Korea
Gazi University Hospital
RECRUITING

Ankara, 06560, Turkey (Türkiye)
Gulhane Training and Research Hospital
RECRUITING

Ankara, 06010, Turkey (Türkiye)
Gundersen Health System
RECRUITING

West Salem, Wisconsin, 54669, United States
Harbin medical university cancer hospital
RECRUITING

Harbin, 150040, China
Henan Cancer Hospital
RECRUITING

Zhengzhou, 450008, China
Hope and Healing Care
RECRUITING

Hinsdale, Illinois, 60521, United States
Hopital Nord
RECRUITING

Marseille, 13915, France
Hopital PASTEUR
RECRUITING

Nice, 06001, France
Hosp Regional Univ de Malaga
RECRUITING

Málaga, 29010, Spain
Hosp Univ A Coruna
RECRUITING

A Coruña, 15006, Spain
Hosp Univ Vall D Hebron
RECRUITING

Barcelona, 08035, Spain
Hosp. Gral. Univ. Gregorio Maranon
RECRUITING

Madrid, 28007, Spain
Hosp. Gral. Univ. de Alicante
RECRUITING

Alicante, 03010, Spain
Hosp. Ntra. Sra. de Valme
RECRUITING

Seville, 41014, Spain
Hosp. Univ. Lucus Augusti
RECRUITING

Lugo, 27003, Spain
Hosp. Univ. Quiron Dexeus
RECRUITING

Barcelona, 08028, Spain
Hosp. Univ. de Jaen
RECRUITING

Jaén, 23007, Spain
Hospital Ana Nery Santa Cruz do Sul
RECRUITING

Santa Cruz do Sul, 96835-100, Brazil
Hospital Italiano de Buenos Aires
RECRUITING

Buenos Aires, C1199, Argentina
Hospital Italiano de La Plata
COMPLETED

La Plata, B1900AXI, Argentina
Hospital Nossa Senhora da Conceicao S A
RECRUITING

Porto Alegre, 91350 200, Brazil
Hospital Privado de la Comunidad
RECRUITING

Mar del Plata, B7602, Argentina
Hospital Pulau Pinang
RECRUITING

George Town, 10450, Malaysia
Hospital Tengku Ampuan Afzan
RECRUITING

Kuantan, 25100, Malaysia
Hospital Umum Sarawak
RECRUITING

Kuching, 93586, Malaysia
Huizhou Municipal Central Hospital
RECRUITING

Huizhou, 516001, China
Hunterdon Hematology Oncology
COMPLETED

Flemington, New Jersey, 08822, United States
I A U VM Medical Park Florya Hastanesi
RECRUITING

Istanbul, 34295, Turkey (Türkiye)
IADT Instituto Argentino de Diagnostico y Tratamiento
RECRUITING

CABA, C1122, Argentina
Institut Curie
RECRUITING

Paris, 75005, France
Ironwood Cancer and Research Center
RECRUITING

Chandler, Arizona, 85224, United States
Kaiser Permanente Northern California
RECRUITING

Vallejo, California, 94589, United States
Kaiser Permanente Oakland Medical Center
RECRUITING

Oakland, California, 94611, United States
Kaiser Permanente Roseville Medical Center
RECRUITING

Roseville, California, 95661, United States
Kaiser Permanente San Francisco Medical Center
RECRUITING

San Francisco, California, 94115, United States
Kaiser Permanente Santa Clara Medical Center
RECRUITING

Santa Clara, California, 95051, United States
Kaiser Permanente Walnut Creek Medical Center
RECRUITING

Walnut Creek, California, 94596, United States
Keck Hospital of USC
RECRUITING

Los Angeles, California, 90033, United States
Kliniken Essen-Mitte
RECRUITING

Essen, 45136, Germany
Klinikum Kassel GmbH
RECRUITING

Kassel, 34125, Germany
Liga Paranaense de Combate ao Cancer
RECRUITING

Curitiba, 81520-060, Brazil
Linkou Chang Gung Memorial Hospital
RECRUITING

Taoyuan City, 333, Taiwan
Los Angeles Cancer Network
RECRUITING

Glendale, California, 91204, United States
National Taiwan University Hospital
RECRUITING

Taipei, 100, Taiwan
National Taiwan University Hospital Hsin Chu Branch
RECRUITING

Hsinchu, 30059, Taiwan
Nucleo de Oncologia da Bahia Oncoclinicas
RECRUITING

Salvador, 40170 070, Brazil
Oncology Hematology Associates
RECRUITING

Springfield, Missouri, 65807, United States
Ondokuz Mayis University
RECRUITING

Samsun, 55420, Turkey (Türkiye)
Providence Fullerton
RECRUITING

Fullerton, California, 92835, United States
Regional Medical Oncology Center
RECRUITING

Wilson, North Carolina, 27893, United States
Renown Health Medical Oncology
RECRUITING

Reno, Nevada, 89502, United States
Santa Casa de Misericordia de Belo Horizonte
RECRUITING

Belo Horizonte, 30150-221, Brazil
Servicos de Tratamento ao Cancer de Taubate LTDA - Instituto do Cancer Brasil Unidade Taubate
RECRUITING

Taubaté, 12030-200, Brazil
Severance Hospital Yonsei University Health System
RECRUITING

Seoul, 03722, South Korea
Sichuan Cancer Hospital
RECRUITING

Chengdu, 610041, China
Taichung Veterans General Hospital
RECRUITING

Taichung, 40705, Taiwan
The First Affiliated Hospital Sun Yat sen University
RECRUITING

Guangzhou, 510080, China
The First Affiliated Hospital Zhejiang University School of Medicine
RECRUITING

Hangzhou, 310003, China
The First Affiliated Hospital of Xian Jiaotong University
RECRUITING

Xi'an, 710061, China
Thoraxklinik am Universitatsklinikum Heidelberg
RECRUITING

Heidelberg, 69126, Germany
USC Norris Oncology Hematology Newport Beach
RECRUITING

Newport Beach, California, 92663, United States
Universitaetsklinikum Giessen und Marburg GmbH
RECRUITING

Giessen, 35392, Germany
Universitaetsklinikum Schleswig Holstein Campus Kiel
RECRUITING

Kiel, 24105, Germany
Universitaetsklinikum der RWTH Aachen
RECRUITING

Aachen, 52074, Germany
University Cancer & Blood Center
RECRUITING

Athens, Georgia, 30607, United States
University Hospitals Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States
University Malaya Medical Centre
RECRUITING

Kuala Lumpur, 59100, Malaysia
Valley Medical Center
COMPLETED

Renton, Washington, 98055, United States
Virginia Cancer Specialists
RECRUITING

Fairfax, Virginia, 22031, United States
West China Hospital
RECRUITING

Chengdoucun, 610041, China
Zhongda Hospital Southeast University
RECRUITING

Nanjing, 210000, China

Conditions

Explore the condition pages connected to this study.

CARCINOMA NON-SMALL-CELL LUNG