New malaria vaccine regimen tested for safety in UK adults

NCT ID NCT06320535

First seen Nov 17, 2025 · Last updated May 14, 2026 · Updated 25 times

Summary

This early-stage study tests whether a new way of giving the R21/Matrix-M™ malaria vaccine is safe and creates a strong immune response. About 36 healthy adults in the UK who have never had malaria will receive either the standard vaccine schedule or an experimental one with increasing doses. The goal is to find a better vaccination plan to protect against malaria.

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Contacts and locations

Locations

  • Centre for Clinical Vaccinology and Tropical Meducine, Churchill Hospital, University of Oxford

    Oxford, Oxfordshire, OX3 7LE, United Kingdom

  • University Hospitals Bristol and Weston NHS Foundation Trust

    Bristol, BS2 8HW, United Kingdom

Conditions

Explore the condition pages connected to this study.