Malaria vaccine plus bednets: a One-Two punch?
NCT ID NCT04327440
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study in Malawi looks at whether giving children the RTS,S malaria vaccine along with special insecticide-treated bednets (PBO nets) can lower malaria infection and spread. About 1,700 children aged 7 months to 10 years took part. The goal is to see how well these two tools work together and to prepare for a larger future study.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- RTS,S/AS01 malaria vaccine and insecticide-treated bednets (PBO nets)
- What this could lead to
- If successful, this could show that combining the RTS,S vaccine with special bednets offers better protection against malaria than either alone.
- What could go wrong
- This is a small, early-phase study focused on feasibility, not a large trial. The vaccine's protection wanes over time, and results may not apply to other regions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Malawi College of Medicine
Blantyre, 3, Malawi