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Can a single dose extend Post-Cesarean pain relief?

NCT ID NCT07773220

Symptom relief Sponsor: Khyber Teaching Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time

Summary

This trial tests whether a single intravenous dose of magnesium sulphate or dexamethasone, given before an ultrasound-guided abdominal nerve block, can improve pain control after a planned cesarean section. Eighty women undergoing the procedure will be randomly assigned to receive one of the two add-ons, and their pain will be tracked for 24 hours. The goal is to see which approach provides longer-lasting relief and reduces the need for extra pain medication.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Magnesium sulphate or dexamethasone given as a single intravenous dose before an ultrasound-guided abdominal nerve block
What this could lead to
If one works better, it could point to a simple, safe way to improve pain relief after cesarean delivery, reducing the need for opioids.
What could go wrong
This is a small, early-stage trial, and results may not apply broadly. Both drugs can have side effects, and the benefit over standard care is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged 18-40 years. * Undergoing elective lower-segment cesarean section under spinal anesthesia. * American Society of Anesthesiologists (ASA) physical status I or II. * Singleton, full-term pregnancy with gestational age of at least 37 weeks. * Willing to provide written informed consent. Exclusion Criteria: * Known allergy or contraindication to magnesium sulphate, dexamethasone, or local anesthetics. * History of chronic pain disorders or regular use of analgesics or opioids. * Neurological, renal, hepatic, or cardiovascular disease. * Pregnancy complications such as pre-eclampsia, eclampsia, or placenta previa. * Intraoperative conversion to general anesthesia. * Inadequate spinal block or failed TAP block. * Refusal to participate in the study.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cesarean section complications

How to take part

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  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

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