Can a magnesium membrane preserve bone and gums better after tooth extraction?
NCT ID NCT07800377
First seen Sep 02, 2026 · Last updated Sep 09, 2026 · Updated 3 times
Summary
This trial tests two membrane materials used during vestibular socket therapy, a technique for placing dental implants right after tooth extraction in the front of the mouth. Thirty adults who need such extractions will receive either a biodegradable magnesium membrane or a cortical lamina membrane, along with immediate implant placement and bone grafting. Researchers will compare changes in facial bone dimensions, soft tissue volume, implant stability, and aesthetic outcomes over six months. The goal is to see which material better preserves the bone and gum tissue needed for a successful, natural-looking implant.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Vestibular Socket Therapy using a biodegradable magnesium membrane or a cortical lamina membrane, with immediate implant placement and bone grafting
- What this could lead to
- If it works, this could point toward a better way to preserve bone and gum tissue after tooth extraction, leading to more stable and natural-looking dental implants.
- What could go wrong
- This is a small, early-stage trial with only 30 participants, so results may not apply to everyone. The magnesium membrane is biodegradable and could break down too quickly or cause unexpected tissue reactions.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age between 18 and 45 years. 2. Requirement for extraction of one or more teeth in the maxillary esthetic zone with Type II extraction sockets. 3. Presence of adequate palatal and apical bone to achieve primary implant stability. 4. Adequate interocclusal restorative space for implant-supported prosthetic rehabilitation. 5. Good oral hygiene and satisfactory plaque control Exclusion Criteria: 1. Acute infection at the intended implant site (e.g., acute abscess or cellulitis). 2. Uncontrolled systemic diseases or medical conditions that may compromise bone healing or osseointegration. 3. History of irradiation to the head and neck region within one year before implant placement. 4. Alcohol or drug abuse. 5. Pregnancy or lactation. 6. Parafunctional habits such as bruxism or clenching. 7. Current smoking or tobacco using. 8. Poor oral hygiene or inability to maintain adequate plaque control.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Outpatient Clinic of the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mansoura University
Al Mansurah, Dakahlia Governorate, 35511, Egypt