Could a simple mineral boost ovulation in PCOS?
NCT ID NCT07766590
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This trial asks whether taking magnesium oxide for three months before the fertility drug letrozole can improve ovulation rates in women with insulin-resistant polycystic ovary syndrome (PCOS). About 60 subfertile women aged 18–35 will either receive magnesium oxide followed by letrozole, or letrozole alone. Researchers will track ovulation, mature follicle development, and endometrial thickness to see if the combination works better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Magnesium oxide followed by letrozole
- What this could lead to
- If it works, this could point toward a simple, low-cost way to boost ovulation and pregnancy chances in women with insulin-resistant PCOS.
- What could go wrong
- This is a small, early-stage trial, so results may not hold up in larger groups. Magnesium may cause digestive side effects, and the added benefit over letrozole alone is unproven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for INSULIN RESISTANT PCOS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Bangladesh Medical University
Dhaka, Shahbag, 1000, Bangladesh