Scientists reprogram Patients' own cells to hunt lung cancer
NCT ID NCT02592577
Summary
This early-stage trial tested a new treatment for advanced lung cancer that has stopped responding to standard therapies. Doctors collected immune cells from 28 patients, genetically modified them in a lab to target cancer, and then infused them back into the patients. The main goals were to find a safe dose and see if these 'reprogrammed' cells could shrink tumors in people with specific genetic markers.
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Contacts and locations
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Locations
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City of Hope
Duarte, California, 91010, United States
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Duke University Medical Center, Duke Cancer Institute
Durham, North Carolina, 27710, United States
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Fox Chase Cancer Center
Philadelphia, Pennsylvania, 19111, United States
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H. Lee Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Hospital Universitario 12 Octubre Avda. de Córdoba s/n
Madrid, Madrid, 28041, Spain
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Hospital Universitario Fundación Jiménez Díaz
Madrid, Madrid, 28040, Spain
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Indiana University Simon Cancer Center
Indianapolis, Indiana, 46033, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Ohio State University Wexner Medical Center
Columbus, Ohio, 43210, United States
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Princess Margaret Cancer Centre
Toronto, Ontario, M5G1X6, Canada
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Stanford Cancer Center
Palo Alto, California, 94304, United States
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Tennessee Oncology- Sarah Cannon Research Institute
Nashville, Tennessee, 37203, United States
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The Christie NHS Foundation Trust
Manchester, M20 4BX, United Kingdom
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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University College Hospital Macmillan Cancer Centre
London, WC1E 6AG, United Kingdom
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University of Maryland, Greenebaum Cancer Center
Baltimore, Maryland, 21157, United States
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University of Miami Sylvester Comprehensive Cancer Center
Miami, Florida, 33136, United States
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Washington University, School of Medicine
St Louis, Missouri, 63110, United States
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Winship Cancer Institute of Emory University
Atlanta, Georgia, 30322, United States
Conditions
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