Sleep apnea mouthpiece showdown: which device wins on comfort?
NCT ID NCT06970171
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests two different mouthpieces (mandibular advancement devices) for people with obstructive sleep apnea who cannot use a CPAP machine. Twenty-eight participants will wear one of the two devices for a year, and researchers will track comfort, side effects like jaw pain, and how well they stick with treatment. The goal is to find out which device is easier to tolerate, helping doctors make better treatment choices.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- mandibular advancement device (MAD)
- What this could lead to
- If successful, this study could help doctors choose the most comfortable and tolerable mouthpiece for sleep apnea patients who cannot use CPAP.
- What could go wrong
- This is a small, early-phase trial with only 28 participants, so results may not apply to everyone. Side effects like jaw pain or bite changes are possible.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Medicine Greifswald, Department of Restorative Dentistry, Periodontology and Endodontology
Greifswald, Mecklenburg-Vorpommern, 17475, Germany
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