New hope for kids with rare, deadly lung disease

NCT ID NCT05167825

Summary

This study tested a drug called macitentan in Japanese children with pulmonary arterial hypertension (PAH), a serious condition where high blood pressure damages the lungs and heart. The main goal was to see if taking the drug for 24 weeks improved how well the heart and lungs worked. It also looked at the drug's safety, how it moved through the body, and its effects on children's ability to be active and their quality of life.

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Contacts and locations

Locations

  • Fukuoka Children's Hospital

    Fukuoka, 813-0017, Japan

  • Hokkaido University Hospital

    Sapporo, 060-8648, Japan

  • Institute of Science Tokyo Hospital

    Bunkyō City, 113 8519, Japan

  • Nagano Children's Hospital

    Azumino-shi, 399-8288, Japan

  • National Center for Child Health and Development

    Setagaya Ku, 157 8535, Japan

  • National Cerebral and Cardiovascular Center

    Suita-Shi, 564-8565, Japan

  • Okayama University Hospital

    Okayama, 700 8558, Japan

  • Osaka University Hospital

    Suita-shi, 565-0871, Japan

  • The University of Tokyo Hospital

    Tokyo, 113-8655, Japan

  • Toho University Medical Center Omori Hospital

    Ōta-ku, 143-8541, Japan

  • Tokyo Women's Medical University Hospital

    Shinjuku-ku, 162-8666, Japan

Conditions

Explore the condition pages connected to this study.