New hope for kids with rare lung condition: drug shows promise in small study
NCT ID NCT05167825
First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 25 times
Summary
This study tested a medicine called macitentan in 7 Japanese children (ages 3 months to 15 years) with pulmonary arterial hypertension, a condition where blood pressure in the lungs is too high. The goal was to see if the drug improves blood flow through the lungs after 24 weeks. The study is complete, and results help doctors understand how the drug works in young patients.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Fukuoka Children's Hospital
Fukuoka, 813-0017, Japan
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Hokkaido University Hospital
Sapporo, 060-8648, Japan
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Institute of Science Tokyo Hospital
Bunkyō City, 113 8519, Japan
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Nagano Children's Hospital
Azumino-shi, 399-8288, Japan
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National Center for Child Health and Development
Setagaya Ku, 157 8535, Japan
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National Cerebral and Cardiovascular Center
Suita-Shi, 564-8565, Japan
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Okayama University Hospital
Okayama, 700 8558, Japan
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Osaka University Hospital
Suita-shi, 565-0871, Japan
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The University of Tokyo Hospital
Tokyo, 113-8655, Japan
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Toho University Medical Center Omori Hospital
Ōta-ku, 143-8541, Japan
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Tokyo Women's Medical University Hospital
Shinjuku-ku, 162-8666, Japan
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.