New hope for kids with high blood pressure in the lungs

NCT ID NCT05167825

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 20 times

Summary

This study tested a medicine called macitentan in 7 Japanese children aged 3 months to 15 years who have pulmonary arterial hypertension, a rare condition where blood pressure in the lungs is too high. The goal was to see if the drug improves blood flow through the lungs after 24 weeks of treatment. The study is complete, but results are not yet available.

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Contacts and locations

Locations

  • Fukuoka Children's Hospital

    Fukuoka, 813-0017, Japan

  • Hokkaido University Hospital

    Sapporo, 060-8648, Japan

  • Institute of Science Tokyo Hospital

    Bunkyō City, 113 8519, Japan

  • Nagano Children's Hospital

    Azumino-shi, 399-8288, Japan

  • National Center for Child Health and Development

    Setagaya Ku, 157 8535, Japan

  • National Cerebral and Cardiovascular Center

    Suita-Shi, 564-8565, Japan

  • Okayama University Hospital

    Okayama, 700 8558, Japan

  • Osaka University Hospital

    Suita-shi, 565-0871, Japan

  • The University of Tokyo Hospital

    Tokyo, 113-8655, Japan

  • Toho University Medical Center Omori Hospital

    Ōta-ku, 143-8541, Japan

  • Tokyo Women's Medical University Hospital

    Shinjuku-ku, 162-8666, Japan

Conditions

Explore the condition pages connected to this study.