New hope for kids with rare, deadly lung disease

NCT ID NCT02932410

Completed Disease control Sponsor: Actelion Source: ClinicalTrials.gov ↗

Summary

This study tested a medication called macitentan in children with pulmonary arterial hypertension (PAH), a serious condition causing high blood pressure in the lungs. It compared the drug to standard care to see if it was safe, worked well in children's bodies, and could help control the disease. The goal was to find a better treatment to slow disease progression and improve children's daily lives.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Bashkiria State Medical University

Ufa, 450000, Russia
Beijing Anzhen Hospital of The Capital University of Medical Sciences

Beijing, 100029, China
Boston Children's Hospital

Boston, Massachusetts, 02115, United States
C.H. Regional Reina Sofia

Córdoba, 14004, Spain
CICUM San Miguel

Guadalajara, 44160, Mexico
Centro Hospitalar E Universitário de Coimbra EPE

Coimbra, 3000-075, Portugal
Centro Hospitalar de Lisboa Ocidental, EPE - Hospital de Santa Cruz

Carnaxide, 2790-134, Portugal
Centro Hospitalar de Sao Joao EPE

Porto, 4200-319, Portugal
Centro Medico Imbanaco de Cali SA

Cali, 760042, Colombia
Chaim Sheba Medical Center

Ramat Gan, 52621, Israel
Children's Heart Center

Las Vegas, Nevada, 89109, United States
Children's Hospital 1

Ho Chi Minh City, 700000, Vietnam
Children's Hospital at Westmead

Westmead, 2145, Australia
Children's National Medical Center

Washington D.C., District of Columbia, 20010, United States
Childrens Hospital Colorado

Aurora, Colorado, 80045, United States
Childrens Hospital of Shanghai

Shanghai, 200062, China
Childrens Hospital of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States
Clinical Hospital №1

Tyumen, 625023, Russia
Columbia University Medical Center - PIN

New York, New York, 10032, United States
Detroit Medical Center

Detroit, Michigan, 48201, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
East Carolina University

Greenville, North Carolina, 27834, United States
Fundacion Santa Fe de Bogota

Bogotá, 220246, Colombia
GBUZ Children's Hospital named after Bashlyaeva Z.A. Moscow

Moscow, 125408, Russia
Gottsegen Gyorgy Orszagos Kardiologiai Intezet

Budapest, 1096, Hungary
Groupe Hospitalier Necker Enfants Malades

Paris, 75743, France
HUS Uusi lastensairaala

Helsinki, 00290, Finland
Hanoi Heart Hospital

Hanoi, 100000, Vietnam
Hanoi Medical University Hospital

Hanoi, 100000, Vietnam
Hospital General Universitario Gregorio Marañon

Madrid, 28009, Spain
Hospital Santa Marta

Lisbon, 1169-024, Portugal
Hospital Universitari i Politecnic La Fe de Valencia

Valencia, 46026, Spain
Hospital Universitario 12 de Octubre

Madrid, 28041, Spain
Hospital Universitario La Paz

Madrid, 28046, Spain
Hospital Universitario Ramon y Cajal

Madrid, 28034, Spain
Hospital Universitario Vall d'Hebron - PPDS

Barcelona, 08035, Spain
Hôpital Des Enfants

Toulouse, 31059, France
Hôpital Haut-Lévêque - Hôpital cardiologique

Pessac, 33604, France
Hôpital de la Timone Enfants

Marseille, 13385, France
Inkosi Albert Luthuli Central Hospital

Durban, 4001, South Africa
Institut Jantung Negara

Kuala Lumpur, 50400, Malaysia
Instituto Nacional de Cardiologia Dr. Ignacio Chavez

Mexico City, 14080, Mexico
Instituto Nacional de Pediatría

Mexico City, 04530, Mexico
Instytut Pomnik - Centrum Zdrowia Dziecka

Warsaw, 04-730, Poland
Irmandade Da Santa Casa de Misericórdia de São Paulo

São Paulo, 01221-020, Brazil
Lady Cilento Children's Hospital

South Brisbane, 4101, Australia
Landes Frauen Und Kinderklinik Linz

Linz, 4020, Austria
MI Dnipropetrovsk Specialized Clin. Med. Center of Mother and Child n.a. prof. M.F. Rudnev of DRC

Dnipro, 49000, Ukraine
MI Scientific Practical Medical Center for Children Cardiology and Cardiosurgery of MOH of Ukraine

Kyiv, 04050, Ukraine
Maharaj Nakorn Chiang Mai Chiang Mai University

Chiang Mai, 50200, Thailand
Makati Medical Center

Makati City, 1229, Philippines
Mayo Clinic - PPDS

Rochester, Minnesota, 55905, United States
Medizinische Universitat Wien

Linz, 4020, Austria
Medizinische Universität Graz

Graz, 8036, Austria
Montefiore Medical Center

The Bronx, New York, 10467, United States
Municipal Institution of Health Care Regional Children's Clinical Hospital

Kharkiv, 61093, Ukraine
Nationwide Children's Hospital

Columbus, Ohio, 43205, United States
Novosibirsk Research Institue of Blood Circulation Pathology n.a. E.N. Meshalkin

Novosibirsk, 630055, Russia
Operadora de Hospitales Angeles SA de CV Hospital Angeles Lomas

México, 52763, Mexico
Philippine Heart Center

Quezon City, 0850, Philippines
Phoenix Childrens Hospital

Phoenix, Arizona, 85016, United States
Primary Children's Medical Center

Salt Lake City, Utah, 84113, United States
Qingdao Women and Children's Hospital

Qingdao, 26600, China
Rambam Medical Center - PPDS

Haifa, 31096, Israel
Research Institute of Complex Cardiovascular Pathology

Kemerovo, 650002, Russia
Riley Hospital For Children

Indianapolis, Indiana, 46202, United States
Royal Children's Hospital Melbourne - PIN

Parkville, 3052, Australia
Russian National Research Medical University n.a. N.I.Pirogov

Moscow, 125412, Russia
Saint Petersburg State Pediatric Medical Academy

Saint Petersburg, 194100, Russia
Sainte Justine Hospital

Montreal, H3T 1C5, Canada
Schneider Children's Medical Center of Israel - PIN

Petah Tikva, 49100, Israel
Seoul National University Hospital

Seoul, 03080, South Korea
Severance Hospital Yonsei University Health System - PPDS

Seoul, 03722, South Korea
Shanghai Children's Medical Center

Shanghai, 200127, China
Szpital Kliniczny im. Karola Jonschera Uniwersytetu Medycznego im. Karola Marcinkowskiego w Poznaniu

Poznan, 60-572, Poland
Tam Duc Hospital

Ho Chi Minh City, 700000, Vietnam
UCLA Children's Heart Center

Los Angeles, California, 90095, United States
UCSF Medical Center

San Francisco, California, 94143-2202, United States
Unidad de Investigación Clínica En Medicina SC

Monterrey, 64716, Mexico
University Hospitals Cleveland Medical Center, Rainbow Babies and Childrens Hospital

Cleveland, Ohio, 44106, United States
University Malaya Medical Centre

Kuala Lumpur, 59100, Malaysia
University of The Free State

Bloemfontein, 9300, South Africa
University of Virginia Health System

Charlottesville, Virginia, 19803, United States
Wojewodzki Szpital Specjalistyczny we Wroclawiu Osrodek Badawczo-Rozwojowy

Wroclaw, 51-124, Poland

Conditions

Explore the condition pages connected to this study.

PULMONARY ARTERIAL HYPERTENSION